Recent progress on the effect of extracellular matrix on occurrence and progression of breast cancer

TY Yu, G Zhang, XX Chai, L Ren, DC Yin, CY Zhang - Life Sciences, 2023 - Elsevier
Breast cancer (BC) metastasis is an enormous challenge targeting BC therapy. The
extracellular matrix (ECM), the principal component of the BC metastasis niche, is the pivotal …

Recent advances on the model, measurement technique, and application of single cell mechanics

H Huang, C Dai, H Shen, M Gu, Y Wang, J Liu… - International Journal of …, 2020 - mdpi.com
Since the cell was discovered by humans, it has been an important research subject for
researchers. The mechanical response of cells to external stimuli and the biomechanical …

Nanoindentation study of the viscoelastic properties of human triple negative breast cancer tissues: implications for mechanical biomarkers

T Ezenwafor, V Anye, J Madukwe, S Amin, J Obayemi… - Acta Biomaterialia, 2023 - Elsevier
This paper presents the results of a combined experimental and theoretical study of the
structure and viscoelastic properties of human non-tumorigenic mammary breast tissues and …

Investigation of creep properties and the cytoskeletal structures of non‐tumorigenic breast cells and triple‐negative breast cancer cells

K Onwudiwe, J Obayemi, J Hu, J Oparah… - … Research Part A, 2022 - Wiley Online Library
This article presents the correlation of creep and viscoelastic properties to the cytoskeletal
structure of both tumorigenic and non‐tumorigenic cells. Unique shear assay and strain …

Actin cytoskeletal structure and the statistical variations of the mechanical properties of non-tumorigenic breast and triple-negative breast cancer cells

K Onwudiwe, J Hu, J Obayemi, V Uzonwanne… - Journal of the …, 2021 - Elsevier
This paper presents the results of a study of the actin cytoskeletal structures and the
statistical variations in the actin fluorescence intensities and viscoelastic properties of non …

Mechanical Perspective on Increasing Brush Cytology Yield

I Khamaysi, R Firman, P Martin, G Vasilyev… - ACS Biomaterials …, 2024 - ACS Publications
Brush cytology is a sampling technique extensively used for mucosal surfaces, particularly to
identify malignancies. A sample is obtained by rubbing the brush bristles over the stricture or …

Microfluidic device reveals new insights into impairment of neutrophil transmigration in patients with sepsis

Y Qi, H Wang, J Wu, R Wang, Z Xu, X Cui… - Biosensors and …, 2024 - Elsevier
Neutrophils need to migrate through tight tissue spaces to eliminate pathogens, but their
movement is often hindered by their large and stiff nuclei. Neutrophil migration is impaired in …

Shear Assay Protocol for the Determination of Single-Cell Material Properties (Video)| JoVE

LJ Holen, K Onwudiwe, J Najera, M Zarodniuk… - JoVE (Journal of …, 2023 - jove.com
Irregular biomechanics are a hallmark of cancer biology subject to extensive study. The
mechanical properties of a cell are similar to those of a material. A cell's resistance to stress …

Adhesion of LHRH/EphA2 to human triple negative breast cancer tissues

TC Ezenwafor, VO Uzonwanne, JUA Madukwe… - Journal of the …, 2022 - Elsevier
The adhesive interactions between molecular recognition units (such as specific peptides
and antibodies) and antigens or other receptors on the surfaces of tumors are of great value …

Difference in biophysical properties of cancer-initiating cells in melanoma mutated zebrafish

N Makarova, V Kalaparthi, A Wang, C Williams… - Journal of the …, 2020 - Elsevier
Despite sharing oncogenetic mutations, only a small number of cells within a given tissue
will undergo malignant transformation. Biochemical and physical factors responsible for this …