[HTML][HTML] Flavonoids against non-physiologic inflammation attributed to cancer initiation, development, and progression—3PM pathways

P Kubatka, A Mazurakova, M Samec, L Koklesova… - Epma Journal, 2021 - Springer
Inflammation is an essential pillar of the immune defense. On the other hand, chronic
inflammation is considered a hallmark of cancer initiation and progression. Chronic …

Cellular and molecular mechanisms of genistein in prevention and treatment of diseases: An overview

F Nazari‐Khanamiri… - Journal of Food …, 2021 - Wiley Online Library
Genistein is the simplest secondary metabolite in soybeans and belongs to a group of
compounds called isoflavones. It is a phytoestrogen and it makes up more than 60% of soy …

Therapeutic effects of genistein in experimentally induced ulcerative colitis in rats via affecting mitochondrial biogenesis

TS Alharbi, ZS Alshammari, ZN Alanzi… - Molecular and Cellular …, 2024 - Springer
Ulcerative colitis (UC) is an inflammatory bowel disease that affects the mucosa of the colon,
resulting in severe inflammation and ulcers. Genistein is a polyphenolic isoflavone present …

[HTML][HTML] Helicobacter pylori infection activates Wnt/β-catenin pathway to promote the occurrence of gastritis by upregulating ASCL1 and AQP5

W Zuo, H Yang, N Li, Y Ouyang, X Xu, J Hong - Cell Death Discovery, 2022 - nature.com
Helicobacter pylori (H. pylori) infection is a well-recognized contributing factor to gastritis, but
the underlying mechanisms remain to be established. It is interesting to note that AQP5 was …

[HTML][HTML] Controlling the Impact of Helicobacter pylori-Related Hyperhomocysteinemia on Neurodegeneration

J Kountouras, M Doulberis, A Papaefthymiou… - Medicina, 2023 - mdpi.com
Helicobacter pylori infection consists a high global burden affecting more than 50% of the
world's population. It is implicated, beyond substantiated local gastric pathologies, ie, peptic …

Profiling of Metabolites in a Fermented Soy Dietary Supplement Reinforces its Role in the Management of Intestinal Inflammation

R Ethier, A Krishnamurthy, M Jeffrey… - Molecular Nutrition & …, 2024 - Wiley Online Library
Scope Gastro‐AD (GAD) is a soy flour derived product that undergoes an industrial
fermentation with Lactobacillus delbrueckii R0187 and has demonstrated clinical effects in …

[HTML][HTML] Fighting the Antibiotic Crisis: Flavonoids as Promising Antibacterial Drugs Against Helicobacter pylori Infection

A González, J Casado, Á Lanas - Frontiers in cellular and infection …, 2021 - frontiersin.org
Over half of the world's population is estimated to be infected with Helicobacter pylori.
Chronic infection with this microbial class I carcinogen is considered the most important risk …

An overview of potential algae-derived bioactive compounds against urease-positive microorganisms

N Oliyaei, MH Hashempur, K Zomorodian, N Tanideh… - Algal Research, 2023 - Elsevier
Abstract Urease (EC 3.5. 1.5) is a virulence factor found in various microorganisms,
including Helicobacter pylori, Proteus mirabilis, and Klebsiella pneumoniae. As a nickel …

[HTML][HTML] Genistein Inhibits the Pathogenesis of Aeromonas hydrophila by Disrupting Quorum Sensing Mediated Biofilm Formation and Aerolysin Production

J Dong, D Zhang, J Li, Y Liu, S Zhou, Y Yang… - Frontiers in …, 2021 - frontiersin.org
Aeromonas hydrophila is an opportunistic pathogen that is responsible for a variety of
infectious diseases both in human and animals, particularly aquatic animals. Moreover, the …

Genistein: Therapeutic and preventive effects, mechanisms, and clinical application in digestive tract tumor

S Hou - Evidence‐Based Complementary and Alternative …, 2022 - Wiley Online Library
Genistein is one of the numerous recognized isoflavones that may be found in a variety of
soybeans and soy products, including tofu and tofu products. The chemical name for …