Airway epithelial barrier dysfunction in chronic obstructive pulmonary disease: role of cigarette smoke exposure

M Aghapour, P Raee, SJ Moghaddam… - American journal of …, 2018 - atsjournals.org
The epithelial lining of the airway forms the first barrier against environmental insults, such
as inhaled cigarette smoke, which is the primary risk factor for the development of chronic …

Mechanisms of lung disease development in rheumatoid arthritis

D Wang, J Zhang, J Lau, S Wang, V Taneja… - Nature Reviews …, 2019 - nature.com
Rheumatoid arthritis (RA) is a chronic autoimmune disorder that causes joint inflammation
and damage. Extra-articular manifestations occur in many patients and can include lung …

Interstitial lung disease and pulmonary fibrosis: a practical approach for general medicine physicians with focus on the medical history

O Kalchiem-Dekel, JR Galvin, AP Burke… - Journal of clinical …, 2018 - mdpi.com
Interstitial lung disease (ILD) and pulmonary fibrosis comprise a wide array of inflammatory
and fibrotic lung diseases which are often confusing to general medicine and pulmonary …

Current concepts in pathogenesis, diagnosis, and management of smoking-related interstitial lung diseases

A Kumar, SV Cherian, R Vassallo, SY Eunhee, JH Ryu - Chest, 2018 - Elsevier
Tobacco exposure results in various changes to the airways and lung parenchyma.
Although emphysema represents the more common injury pattern, in some individuals …

Bacterial biomarkers capable of identifying recurrence or metastasis carry disease severity information for lung cancer

X Yuan, Z Wang, C Li, K Lv, G Tian, M Tang… - Frontiers in …, 2022 - frontiersin.org
Background Local recurrence and distant metastasis are the main causes of death in
patients with lung cancer. Multiple studies have described the recurrence or metastasis of …

Oxidative stress and lung fibrosis: towards an adverse outcome pathway

P Makena, T Kikalova, GL Prasad… - International Journal of …, 2023 - mdpi.com
Lung fibrosis is a progressive fatal disease in which deregulated wound healing of lung
epithelial cells drives progressive fibrotic changes. Persistent lung injury due to oxidative …

Risk factors for the development of idiopathic pulmonary fibrosis: a review

T Zaman, JS Lee - Current pulmonology reports, 2018 - Springer
Abstract Purpose of Review Idiopathic pulmonary fibrosis (IPF) is an invariably progressive
disease. Current treatment options simply slow disease progression, and better therapeutic …

The effects of cigarette smoking extracts on cell cycle and tumor spread: novel evidence

A Pezzuto, F Citarella, I Croghan, G Tonini - Future science OA, 2019 - Taylor & Francis
Cigarette smoking is a major preventable risk factor for lung cancer, contributing to lung
cancer progression and metastasis. Moreover, cigarette smoking correlates with increased …

E‐cigarette vapor induces an apoptotic response in human gingival epithelial cells through the caspase‐3 pathway

M Rouabhia, HJ Park, A Semlali… - Journal of cellular …, 2017 - Wiley Online Library
Electronic cigarettes represent an increasingly significant proportion of today's consumable
tobacco products. E‐cigarettes contain several chemicals which may promote oral diseases …

Impact of smoking on the development of idiopathic pulmonary fibrosis: results from a nationwide population-based cohort study

W Bae, CH Lee, J Lee, YW Kim, K Han, SM Choi - Thorax, 2022 - thorax.bmj.com
Background Smoking has been considered an important risk factor for idiopathic pulmonary
fibrosis (IPF) incidence. However, there are no population-based large-scale studies …