The activity-regulated cytoskeletal (Arc) gene encodes a protein that is critical for memory
consolidation. Arc is one of the most tightly regulated molecules known: neuronal activity …

The immediate early gene Arc is emerging as a versatile, finely tuned system capable of
coupling changes in neuronal activity patterns to synaptic plasticity, thereby optimizing …

Emotional arousal enhances perception and memory of high-priority information but impairs
processing of other information. Here, we propose that, under arousal, local glutamate levels …

The brain is a highly adaptable organ that is capable of converting sensory information into
changes in neuronal function. This plasticity allows behavior to be accommodated to the …

The activity-regulated cytoskeletal protein Arc (also known as Arg3. 1) is required for long-
term memory formation and synaptic plasticity. Arc expression is robustly induced by activity …

Considerable evidence indicates that glucocorticoid hormones enhance the consolidation of
memory for emotionally arousing events through interactions with the noradrenergic system …

Memory consolidation requires transcription and translation of new protein. Arc, an effector
immediate early gene, and zif268, a regulatory transcription factor, have been implicated in …

We tested the hypothesis that excess saturated fat consumption during pregnancy, lactation,
and/or postweaning alters the expression of genes mediating hippocampal synaptic efficacy …

A product of the immediate early gene Arc (Activity-regulated cytoskeleton-associated
protein or Arc protein) of retroviral ancestry resides in the genome of all tetrapods for millions …

Major depressive disorder (MDD) is primarily conceptualized as a mood disorder but
cognitive dysfunction is also prevalent, and may limit the daily function of MDD patients …