We propose a novel mathematical and numerical model for cardiac electromechanics,
wherein biophysically detailed core models describe the different physical processes …

In this work, we present a fully coupled fluid‐electro‐mechanical model of a 50th percentile
human heart. The model is implemented on Alya, the BSC multi‐physics parallel code …

The pericardium affects cardiac motion by limiting epicardial displacement normal to the
surface. In computational studies, it is important for the model to replicate realistic motion, as …

Cardiac resynchronisation therapy (CRT) has an established role in the management of
patients with heart failure, reduced left ventricular ejection fraction (LVEF< 35%) and …

Cardiovascular diseases account for the number one cause of deaths in the world. Part of
the reason for such grim statistics is our limited understanding of the underlying mechanisms …

In this study we present a novel computational model for unprecedented simulations of the
whole cardiac electrophysiology. According to the heterogeneous electrophysiologic …

Single ventricle patients, including those with hypoplastic left heart syndrome (HLHS),
typically undergo three palliative heart surgeries culminating in the Fontan procedure. HLHS …

Background: Up to 30–50% of chronic heart failure patients who underwent cardiac
resynchronization therapy (CRT) do not respond to the treatment. Therefore, patient …

Cardiac resynchronization therapy (CRT) is an established treatment for left bundle branch
block (LBBB) resulting in mechanical dyssynchrony. Approximately 1/3 of patients with CRT …

Mechanical dyssynchrony affects left ventricular (LV) mechanics and coronary perfusion.
Due to the confounding effects of their bi-directional interactions, the mechanisms behind …