The protein kinase ataxia telangiectasia mutated (ATM) is a master regulator of double-
strand DNA break (DSB) signalling and stress responses. For three decades, ATM has been …

Central nervous system (CNS) disorders affect as many as 1.5 billion people globally. The
limited delivery of most imaging and therapeutic agents into the brain is a major challenge …

It is generally thought that under basal conditions, neurons produce ATP mainly through
mitochondrial oxidative phosphorylation (OXPHOS), and glycolytic activity only …

The importance of nutrition in human health has been understood for over a century.
However, debate is ongoing regarding the role of added and free sugars in physiological …

Manganese is an essential trace metal. The dysregulation of manganese seen in a broad
spectrum of neurological disorders reflects its importance in brain development and key …

Targeting SIRT1 signaling pathway could improve glucose aerobic metabolism and
mitochondrial biosynthesis to resist cardiac and neurological injuries. Ginsenoside Rc has …

Most photoacoustic (PA) imaging agents are based on the repurposing of existing
fluorescent dye platforms that exhibit non‐optimal properties for PA applications. Herein, we …

Neonicotinoids are a class of insecticides that exert their effect through a specific action on
neuronal nicotinic acetylcholine receptors (nAChRs). The success of these insecticides is …

Astroglia represent a class of heterogeneous, in form and function, cells known as
astrocytes, which provide for homoeostasis and defence of the central nervous system …

Background In ischemic stroke, the function of the cerebral vasculature is impaired. This
vascular structure is formed by the so-called neurovascular unit (NVU). A better …