Allergen immunotherapy is a cornerstone in the treatment of allergic children. The clinical
efficiency relies on a well‐defined immunologic mechanism promoting regulatory T cells and …

During the past years, there has been a global outbreak of allergic diseases, presenting a
considerable medical and socioeconomical burden. A large fraction of allergic diseases is …

Abstract Purpose of Review Allergic rhinitis (AR) is a chronic inflammatory immunoglobulin
(Ig) E-mediated disease of the nasal mucosa that can be triggered by the inhalation of …

abstract Allergen-specific immunotherapy (AIT) is the mainstay treatment for the cure of
allergic disorders, with depicted efficacy and safety by several trials and meta-analysis. AIT …

Modern health care requires a proactive and individualized response to diseases,
combining precision diagnosis and personalized treatment. Accordingly, the approach to …

Allergic rhinitis (AR) is an upper airway disease with high prevalence in the world, and
therefore needs to be thoroughly investigated and treated accordingly. Although the …

Allergen immunotherapy (AIT) is the sole disease-modifying treatment for allergic rhinitis; it
prevents rhinitis from progressing to asthma and lowers medication use. AIT against mites …

Progressive knowledge of allergenic structures resulted in a broad availability of allergenic
molecules for diagnosis. Component‐resolved diagnosis allowed a better understanding of …

The molecular and cellular mechanisms of allergen tolerance in humans have been
intensively studied in the past few decades. The demonstration of epitope-specific T cell …

Background While treatment for atopic rhinitis is aimed mostly to relieve symptoms, only
allergen‐specific immunotherapy (AIT) is targeted to modify the natural history of allergic …