Emergence of SARS-CoV-2 Omicron (B. 1.1. 529) variant, salient features, high global health concerns and strategies to counter it amid ongoing COVID-19 pandemic

R Khandia, S Singhal, T Alqahtani, MA Kamal… - Environmental …, 2022 - Elsevier
Since the appearance in the late of December 2019, SARS-CoV-2 is rapidly evolving and
mutating continuously, giving rise to various variants with variable degrees of infectivity and …

SARS-CoV-2 Omicron variants: burden of disease, impact on vaccine effectiveness and need for variant-adapted vaccines

S Pather, SA Madhi, BJ Cowling, P Moss… - Frontiers in …, 2023 - frontiersin.org
The highly transmissible Omicron (B. 1.1. 529) variant of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) was first detected in late 2021. Initial Omicron waves were …

Omicron SARS-CoV-2 variant: What we know and what we don't

VM Ferré, N Peiffer-Smadja, B Visseaux… - … , critical care & pain …, 2021 - pmc.ncbi.nlm.nih.gov
World Health Organization (WHO) designated the variant B. 1.1. 529 named Omicron as a
variant of concern (VOC) on the 26th of November 2021 [1]. A relative rise in cases of people …

Molecular characteristics, immune evasion, and impact of SARS-CoV-2 variants

C Sun, C Xie, GL Bu, LY Zhong, MS Zeng - Signal Transduction and …, 2022 - nature.com
The persistent COVID-19 pandemic since 2020 has brought an enormous public health
burden to the global society and is accompanied by various evolution of the virus genome …

SARS‐CoV‐2 Omicron variant: Immune escape and vaccine development

D Ao, T Lan, X He, J Liu, L Chen, DT Baptista‐Hon… - MedComm, 2022 - Wiley Online Library
New genetic variants of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)
constantly emerge through unmitigated spread of the virus in the ongoing Coronavirus …

[HTML][HTML] Strong humoral immune responses against SARS-CoV-2 Spike after BNT162b2 mRNA vaccination with a 16-week interval between doses

A Tauzin, SY Gong, G Beaudoin-Bussières, D Vézina… - Cell host & …, 2022 - cell.com
The standard regimen of the BNT162b2 mRNA vaccine for SARS-CoV-2 includes two doses
administered three weeks apart. However, some public health authorities spaced these …

The Omicron variant of concern: Diversification and convergent evolution in spike protein, and escape from anti-Spike monoclonal antibodies

D Focosi, S McConnell, A Casadevall - Drug Resistance Updates, 2022 - Elsevier
Abstract WHO-defined SARS-CoV-2 variants of concern (VOC) drive therapeutics and
vaccine development. The Omicron VOC is dominating the arena since November 2021, but …

[HTML][HTML] Omicron variant: Current insights and future directions

R Rana, R Kant, RS Huirem, D Bohra… - Microbiological …, 2022 - Elsevier
The global COVID-19 outbreak has returned with the identification of the SARS-CoV-2
Omicron variant (B. 1.1. 529) after appearing to be persistently spreading for the more than …

Omicron variant of the SARS-CoV-2: a quest to define the consequences of its high mutational load

J Quarleri, V Galvan, MV Delpino - GeroScience, 2022 - Springer
Accepted: 13 December 2021© The Author (s), under exclusive licence to American Aging
Association 2021 2021, this group was organized to analyze the emergence of the new …

Update on SARS-CoV-2 omicron variant of concern and its peculiar mutational profile

M Alkhatib, R Salpini, L Carioti, FA Ambrosio… - Microbiology …, 2022 - Am Soc Microbiol
The process of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genetic
diversification is still ongoing and has very recently led to the emergence of a new variant of …