This document reviews 1) the measurement properties of commonly used exercise tests in
patients with chronic respiratory diseases and 2) published studies on their utilty and/or …

The American Thoracic Society/European Respiratory Society jointly created a Task Force
on “Outcomes for COPD pharmacological trials: from lung function to biomarkers” to inform …

Cardiopulmonary exercise testing (CPET) is an established method for evaluating dyspnea
and ventilatory abnormalities. Ventilatory reserve is typically assessed as the ratio of peak …

The purpose of this study was to compare the mechanics of breathing including the
measurement of expiratory flow limitation, end‐expiratory lung volume, end‐inspiratory lung …

Fashions in ideas, like clothes, come and go. From approximately 1950–1980, physiological
research was seen as the key discipline in understanding lung disease and was at the …

The main complaint of patients with chronic obstructive pulmonary disease (COPD) is
shortness of breath with exercise, that is usually progressive. The principal mechanism that …

A high proportion of patients with chronic obstructive pulmonary disease (COPD) experience
problems during the performance of activities of daily living (ADLs). We aimed to determine …

Rationale: Ambulatory oxygen improves acute exercise performance in people with chronic
obstructive pulmonary disease (COPD). This improvement may not translate into …

Background Most patients with severe COPD are limited by dyspnea and are obliged to
exercise at low intensity. Even those undergoing training do not usually have increased …

Rationale: Hyperoxia and normoxic helium independently reduce dynamic hyperinflation
and improve the exercise tolerance of patients with chronic obstructive pulmonary disease …