Metabolic engineering of Escherichia coli: a sustainable industrial platform for bio-based chemical production
In order to decrease carbon emissions and negative environmental impacts of various
pollutants, more bulk and/or fine chemicals are produced by bioprocesses, replacing the …
pollutants, more bulk and/or fine chemicals are produced by bioprocesses, replacing the …
[HTML][HTML] Cellular factories for coenzyme Q10 production
SQE Lee, TS Tan, M Kawamukai, ES Chen - Microbial cell factories, 2017 - Springer
Abstract Coenzyme Q 10 (CoQ 10), a benzoquinone present in most organisms, plays an
important role in the electron-transport chain, and its deficiency is associated with various …
important role in the electron-transport chain, and its deficiency is associated with various …
Biosynthesis and bioproduction of coenzyme Q10 by yeasts and other organisms
M Kawamukai - Biotechnology and applied biochemistry, 2009 - Wiley Online Library
CoQ (coenzyme Q), an isoprenylated benzoquinone, is a well‐known component of the
electron‐transfer system in eukaryotes. The main role of CoQ is to transfer electrons from …
electron‐transfer system in eukaryotes. The main role of CoQ is to transfer electrons from …
Current prospects for the production of coenzyme Q10 in microbes
CP Cluis, AM Burja, VJJ Martin - Trends in biotechnology, 2007 - cell.com
Coenzyme Q or ubiquinone (UQ) is a naturally occurring coenzyme formed from the
conjugation of a benzoquinone ring and an isoprenoid chain of varying length. UQ-10, the …
conjugation of a benzoquinone ring and an isoprenoid chain of varying length. UQ-10, the …
Biosynthesis and applications of prenylquinones
M Kawamukai - Bioscience, biotechnology, and biochemistry, 2018 - academic.oup.com
Prenylquinones are isoprenoid compounds with a characteristic quinone structure and
isoprenyl tail that are ubiquitous in almost all living organisms. There are four major …
isoprenyl tail that are ubiquitous in almost all living organisms. There are four major …
Production of coenzyme Q10 by purple non-sulfur bacteria: current development and future prospect
S He, H Lu, G Zhang, Z Ren - Journal of Cleaner Production, 2021 - Elsevier
Abstract Coenzyme Q10 (CoQ10) is extensively used in the fields of medicine, cosmetics,
food, and health care due to its function as an adenosine triphosphate (ATP) synthesis …
food, and health care due to its function as an adenosine triphosphate (ATP) synthesis …
Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily
FH Wallrapp, JJ Pan, G Ramamoorthy… - Proceedings of the …, 2013 - National Acad Sciences
The number of available protein sequences has increased exponentially with the advent of
high-throughput genomic sequencing, creating a significant challenge for functional …
high-throughput genomic sequencing, creating a significant challenge for functional …
Identification of bottlenecks in Escherichia coli engineered for the production of CoQ10
CP Cluis, A Ekins, L Narcross, H Jiang, ND Gold… - Metabolic …, 2011 - Elsevier
In this work, Escherichia coli was engineered to produce a medically valuable cofactor,
coenzyme Q10 (CoQ10), by removing the endogenous octaprenyl diphosphate synthase …
coenzyme Q10 (CoQ10), by removing the endogenous octaprenyl diphosphate synthase …
Production of Coenzyme Q10 by microbes: an update
J Fan, W Xu, X Xu, Y Wang - World Journal of Microbiology and …, 2022 - Springer
Abstract Coenzyme Q10 (CoQ10) is the main CoQ species in human and is used
extensively in food, cosmetic and medicine industries because of its antioxidant properties …
extensively in food, cosmetic and medicine industries because of its antioxidant properties …
Industrial Biotechnology: Escherichia coli as a Host
Escherichia coli has many advantages as a microbial platform for industrial applications.
This chapter summarizes a few examples of E. coli metabolic engineering efforts reported in …
This chapter summarizes a few examples of E. coli metabolic engineering efforts reported in …