NF‐κB signaling in inflammation and cancer

T Zhang, C Ma, Z Zhang, H Zhang, H Hu - MedComm, 2021 - Wiley Online Library
Since nuclear factor of κ‐light chain of enhancer‐activated B cells (NF‐κB) was discovered
in 1986, extraordinary efforts have been made to understand the function and regulating …

Cancers associated with human gammaherpesviruses

KW Wen, L Wang, JR Menke, B Damania - The FEBS journal, 2022 - Wiley Online Library
Epstein–Barr virus (EBV; human herpesvirus 4; HHV‐4) and Kaposi sarcoma‐associated
herpesvirus (KSHV; human herpesvirus 8; HHV‐8) are human gammaherpesviruses that …

Possible cancer-causing capacity of COVID-19: Is SARS-CoV-2 an oncogenic agent?

K Jahankhani, F Ahangari, IM Adcock, E Mortaz - Biochimie, 2023 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has shown diverse life-
threatening effects, most of which are considered short-term. In addition to its short-term …

NF-κB and human cancer: what have we learned over the past 35 years?

TD Gilmore - Biomedicines, 2021 - mdpi.com
Transcription factor NF-κB has been extensively studied for its varied roles in cancer
development since its initial characterization as a potent retroviral oncogene. It is now clear …

Tracking the Endosomal Escape of Nanoparticles in Live Cells Using a Triplex‐Forming Oligonucleotide

SK Bhangu, L Mummolo, S Fernandes… - Advanced Functional …, 2024 - Wiley Online Library
Nanoparticle‐mediated intracellular delivery of oligonucleotides is a complex phenomenon
that depends on the architecture and the intracellular trafficking of the engineered …

Berberine in human oncogenic herpesvirus infections and their linked cancers

M Šudomová, K Berchová-Bímová, S Marzocco… - Viruses, 2021 - mdpi.com
Human herpesviruses are known to induce a broad spectrum of diseases, ranging from
common cold sores to cancer, and infections with some types of these viruses, known as …

Nanotechnology Frontiers in γ-herpesviruses treatments

M Granato - International Journal of Molecular Sciences, 2021 - mdpi.com
Epstein–Barr Virus (EBV) and Kaposi's sarcoma associated-herpesvirus (KSHV) are γ-
herpesviruses that belong to the Herpesviridae family. EBV infections are linked to the onset …

Upregulation of interleukin-6 in HPV-positive breast cancer patients

J Charostad, A Azaran, M Nakhaei, A Astani… - Iranian Journal of …, 2021 - iji.sums.ac.ir
Background: Interleukin-6 (IL-6) is a well-known proinflammatory cytokine with tumor
promoting capacity in various forms of malignancies including breast cancer (BC). Data …

NF-κB: a mediator that promotes or inhibits angiogenesis in human diseases?

Y Jiang, J Zhang, C Shi, X Li, Y Jiang… - Expert Reviews in …, 2023 - cambridge.org
The nuclear factor of κ-light chain of enhancer-activated B cells (NF-κB) signaling pathway,
which is conserved in invertebrates, plays a significant role in human diseases such as …

The ingenol-based protein kinase C agonist GSK445A is a potent inducer of HIV and SIV RNA transcription

AA Okoye, R Fromentin, H Takata, JH Brehm… - PLoS …, 2022 - journals.plos.org
Activation of the NF-κB signaling pathway by Protein Kinase C (PKC) agonists is a potent
mechanism for human immunodeficiency virus (HIV) latency disruption in vitro. However …