The lungs are constantly exposed to inhaled debris, allergens, pollutants, commensal or
pathogenic microorganisms, and respiratory viruses. As a result, innate and adaptive …

The last decade has been somewhat of a renaissance period for the field of macrophage
biology. This renewed interest, combined with the advent of new technologies and …

Intercellular communication is a critical process that ensures cooperation between distinct
cell types and maintains homeostasis. EVs, which were initially described as cellular debris …

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are common life-
threatening lung diseases associated with acute and severe inflammation. Both have high …

Inflammatory monocytes and tissue-resident macrophages are key regulators of tissue
repair, regeneration, and fibrosis. After tissue injury, monocytes and macrophages undergo …

Asthma is a chronic disease of the airways, which affects more than 350 million people
worldwide. It is the most common chronic disease in children, affecting at least 30 million …

The main function of the lung is to perform gas exchange while maintaining lung
homeostasis despite environmental pathogenic and non-pathogenic elements contained in …

Pathogen persistence in the respiratory tract is an important preoccupation, and of particular
relevance to infectious diseases such as tuberculosis. The equilibrium between elimination …

Macrophages are tissue-resident or infiltrated immune cells critical for innate immunity,
normal tissue development, homeostasis, and repair of damaged tissue. Macrophage …

Innate immunity is a rapidly evolving field with novel cell types and molecular pathways
being discovered and paradigms changing continuously. Innate and adaptive immune …