Myelin is critical in maintaining electrical impulse conduction in the central nervous system.
The oligodendrocyte is the cell type responsible for myelin production within this …

Low oxygen concentrations (hypoxia) occur in several physiological and pathological
cellular situations such as embryogenesis and stem cell modulation (in terms of …

Multiple sclerosis (MS) is the most common demyelinating and an autoimmune disease of
the central nervous system characterized by immune-mediated myelin and axonal damage …

Despite improving rates of survival after traumatic brain injury (TBI), many head-injured
patients incur permanent neurologic impairment. Each year in the United States …

Abstract Purpose of Review Traumatic brain injury (TBI) is a global public health concern,
with limited treatment options available. Despite improving survival rate after TBI, treatment …

Neurodegenerative disorders are caused by the death and dysfunction of brain cells, but
despite a huge worldwide effort, no neuroprotective treatments that slow cell death currently …

There is considerable public concern that the majority of commercial chemicals have not
been evaluated for their potential to cause developmental neurotoxicity. Although several …

Increasing evidence points to accelerated neurogenesis after stroke, and support of such
endogenous neurogenesis has been shown to improve stroke outcome in experimental …

Researchers who have uncovered the presence of stem cells in an adult's central nervous
system have not only challenged the dogma that new neurons cannot be generated during …

In vitro, high-throughput methods have been widely recommended as an approach to
screen chemicals for the potential to cause developmental neurotoxicity and prioritize them …