Biomimetic natural biomaterials for tissue engineering and regenerative medicine: new biosynthesis methods, recent advances, and emerging applications
Biomimetic materials have emerged as attractive and competitive alternatives for tissue
engineering (TE) and regenerative medicine. In contrast to conventional biomaterials or …
engineering (TE) and regenerative medicine. In contrast to conventional biomaterials or …
Uncovering the structure–function relationship in spider silk
All spiders produce protein-based biopolymer fibres that we call silk. The most studied of
these silks is spider dragline silk, which is very tough and relatively abundant compared with …
these silks is spider dragline silk, which is very tough and relatively abundant compared with …
1000 spider silkomes: Linking sequences to silk physical properties
Spider silks are among the toughest known materials and thus provide models for
renewable, biodegradable, and sustainable biopolymers. However, the entirety of their …
renewable, biodegradable, and sustainable biopolymers. However, the entirety of their …
Protein secondary structure in spider silk nanofibrils
Nanofibrils play a pivotal role in spider silk and are responsible for many of the impressive
properties of this unique natural material. However, little is known about the internal …
properties of this unique natural material. However, little is known about the internal …
[HTML][HTML] Tuning the conformation and mechanical properties of silk fibroin hydrogels
Mechanical properties of biomaterials play an important role in their biological performance.
Among the most important parameters in designing of biomaterials, their structure and …
Among the most important parameters in designing of biomaterials, their structure and …
Spider silk fibers spun from soluble recombinant silk produced in mammalian cells
A Lazaris, S Arcidiacono, Y Huang, JF Zhou, F Duguay… - science, 2002 - science.org
Spider silks are protein-based “biopolymer” filaments or threads secreted by specialized
epithelial cells as concentrated soluble precursors of highly repetitive primary sequences …
epithelial cells as concentrated soluble precursors of highly repetitive primary sequences …
Multicomponent nature underlies the extraordinary mechanical properties of spider dragline silk
N Kono, H Nakamura, M Mori… - Proceedings of the …, 2021 - National Acad Sciences
Dragline silk of golden orb-weaver spiders (Nephilinae) is noted for its unsurpassed
toughness, combining extraordinary extensibility and tensile strength, suggesting industrial …
toughness, combining extraordinary extensibility and tensile strength, suggesting industrial …
The molecular structure of spider dragline silk: folding and orientation of the protein backbone
JD Van Beek, S Hess, F Vollrath… - Proceedings of the …, 2002 - National Acad Sciences
The design principles of spider dragline silk, nature's high-performance fiber, are still largely
unknown, in particular for the noncrystalline glycine-rich domains, which form the bulk of the …
unknown, in particular for the noncrystalline glycine-rich domains, which form the bulk of the …
Composite materials based on silk proteins
JG Hardy, TR Scheibel - Progress in Polymer Science, 2010 - Elsevier
A number of animals have evolved to produce silk-based composite materials for a variety of
task-specific applications. The review initially focuses on the composite structure of silk …
task-specific applications. The review initially focuses on the composite structure of silk …
Protein secondary structure and orientation in silk as revealed by Raman spectromicroscopy
Taking advantage of recent advances in polarized Raman microspectroscopy, and based on
a rational decomposition of the amide I band, the conformation and orientation of proteins …
a rational decomposition of the amide I band, the conformation and orientation of proteins …