Potassium channel blockers in multiple sclerosis: neuronal Kv channels and effects of symptomatic treatment

SIV Judge, CT Bever Jr - Pharmacology & therapeutics, 2006 - Elsevier
Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS)
characterized by demyelination, with a relative sparing of axons. In MS patients, many …

Novel drug targets for the pharmacotherapy of benign prostatic hyperplasia (BPH)

S Ventura, VL Oliver, CW White, JH Xie… - British journal of …, 2011 - Wiley Online Library
Benign prostatic hyperplasia (BPH) is the major cause of lower urinary tract symptoms in
men aged 50 or older. Symptoms are not normally life threatening, but often drastically affect …

Functions of ICC‐like cells in the urinary tract and male genital organs

H Hashitani, RJ Lang - Journal of cellular and molecular …, 2010 - Wiley Online Library
Overview• Individual organs‐ICC‐LCs in the bladder‐ICC‐LCs in the urethra‐ICC‐LCs in
the penis‐ICC‐LCs in the upper urinary tract‐ICC‐LCs in the prostate• Future of ICC‐LCs …

Electrical characterization of interstitial cells of Cajal-like cells and smooth muscle cells isolated from the mouse ureteropelvic junction

RJ Lang, BZ Zoltkowski, JM Hammer… - The Journal of …, 2007 - auajournals.org
Purpose: We characterized membrane currents in smooth muscle cells and interstitial cells
freshly isolated from the mouse ureteropelvic junction. Materials and Methods: Interstitial …

Effects of Schisandra chinensis extract on the relaxation of isolated human prostate tissue and smooth muscle cell

SH Choo, HH Sung, MR Chae, SJ Kang… - Journal of …, 2014 - Elsevier
Ethnopharmacological relevance Schisandra chinensis has been commonly used as a
traditional herbal medicine to treat various diseases including body weakness, dysentery …

Characteristics of IA currents in adult rabbit cerebellar Purkinje cells

D Wang, BG Schreurs - Brain research, 2006 - Elsevier
Classical conditioning the rabbit nictitating membrane involves changes in synaptic and
intrinsic membrane properties of cerebellar Purkinje cell dendrites, and a 4-aminopyridine (4 …

Inositol trisphosphate‐dependent Ca2+ stores and mitochondria modulate slow wave activity arising from the smooth muscle cells of the guinea pig prostate gland

B Exintaris, DTT Nguyen, M Lam… - British journal of …, 2009 - Wiley Online Library
Background and purpose: Changes in smooth muscle tone of the prostate gland are
involved in aetiology of symptomatic prostatic hyperplasia, however the control mechanisms …

T-type Ca2+ channels and the urinary and male genital tracts

CH Fry, RI Jabr - Pflügers Archiv-European Journal of Physiology, 2014 - Springer
T-type Ca 2+ channels are widely expressed throughout the urinary and male genital tracts,
generally alongside L-type Ca 2+ channels. The use of pharmacological blockers of these …

Voltage‐operated Ca2+ currents and Ca2+‐activated Cl currents in single interstitial cells of the guinea‐pig prostate

RJ Lang, MA Tonta, H Takano, H Hashitani - BJU international, 2014 - Wiley Online Library
Objective To investigate the expression of 'T‐type'and 'L‐type'voltage‐operated Ca2+
channels in single interstitial cells of the guinea‐pig prostate. Material and Methods Whole …

Spontaneous Ca2+ Signaling of Interstitial Cells in the Guinea Pig Prostate

M Lam, Y Shigemasa, B Exintaris, RJ Lang… - The Journal of …, 2011 - auajournals.org
Purpose: We investigated whether prostate interstitial cells generate spontaneous Ca2+
oscillation, a proposed mechanism underlying pacemaker potentials to drive spontaneous …