Targeting the tumor stroma for cancer therapy

M Xu, T Zhang, R Xia, Y Wei, X Wei - Molecular Cancer, 2022 - Springer
Tumors are comprised of both cancer cells and surrounding stromal components. As an
essential part of the tumor microenvironment, the tumor stroma is highly dynamic …

Therapeutic potential of mesenchymal stem cells for cancer therapy

A Hmadcha, A Martin-Montalvo, BR Gauthier… - … in bioengineering and …, 2020 - frontiersin.org
Mesenchymal stem cells (MSCs) are among the most frequently used cell type for
regenerative medicine. A large number of studies have shown the beneficial effects of MSC …

Nanomaterials for diagnosis and treatment of brain cancer: Recent updates

M Mukhtar, M Bilal, A Rahdar, M Barani, R Arshad… - Chemosensors, 2020 - mdpi.com
Brain tumors, especially glioblastoma, remain the most aggressive form of all the cancers
because of inefficient diagnosis and profiling. Nanostructures, such as metallic …

Quantification of extracellular vesicles in vitro and in vivo using sensitive bioluminescence imaging

D Gupta, X Liang, S Pavlova… - Journal of …, 2020 - Taylor & Francis
Extracellular vesicles (EVs) are naturally occurring nano-sized carriers that are secreted by
cells and facilitate cell-to-cell communication by their unique ability to transfer biologically …

Application of mesenchymal stem cells for therapeutic agent delivery in anti-tumor treatment

DS Chulpanova, KV Kitaeva, LG Tazetdinova… - Frontiers in …, 2018 - frontiersin.org
Mesenchymal stem cells (MSCs) are non-hematopoietic progenitor cells, which can be
isolated from different types of tissues including bone marrow, adipose tissue, tooth pulp …

Genetic engineering as a strategy to improve the therapeutic efficacy of mesenchymal stem/stromal cells in regenerative medicine

PKF Damasceno, TSA De Santana… - Frontiers in Cell and …, 2020 - frontiersin.org
Mesenchymal stem/stromal cells (MSCs) have been widely studied in the field of
regenerative medicine for applications in the treatment of several disease settings. The …

An Update on in Vivo Imaging of Extracellular Vesicles as Drug Delivery Vehicles

P Gangadaran, CM Hong, BC Ahn - Frontiers in pharmacology, 2018 - frontiersin.org
Extracellular vesicles (EVs) are currently being considered as promising drug delivery
vehicles. EVs are naturally occurring vesicles that exhibit many characteristics favorable to …

Bioengineered cellular and cell membrane-derived vehicles for actively targeted drug delivery: so near and yet so far

MY Thanuja, C Anupama, SH Ranganath - Advanced drug delivery reviews, 2018 - Elsevier
Cellular carriers for drug delivery are attractive alternatives to synthetic nanoparticles owing
to their innate homing/targeting abilities. Here, we review molecular interactions involved in …

Mesenchymal stem cells: A living carrier for active tumor-targeted delivery

T Zhang, R Lin, H Wu, X Jiang, J Gao - Advanced Drug Delivery Reviews, 2022 - Elsevier
The strategy of using mesenchymal stem cells (MSCs) as a living carrier for active delivery of
therapeutic agents targeting tumor sites has been attempted in a wide range of studies to …

The future of mesenchymal stem cell-based therapeutic approaches for cancer–from cells to ghosts

A Mohr, R Zwacka - Cancer letters, 2018 - Elsevier
Mesenchymal stem cells (MSCs) are multipotent stromal cells which can differentiate into a
variety of cell types including osteoblasts, adipocytes and chondrocytes. They are normally …