Mechanisms of bone remodeling and therapeutic strategies in chronic apical periodontitis

X Luo, Q Wan, L Cheng, R Xu - Frontiers in cellular and infection …, 2022 - frontiersin.org
Chronic periapical periodontitis (CAP) is a typical oral disease in which periodontal
inflammation caused by an odontogenic infection eventually leads to bone loss …

Oral osteomicrobiology: the role of oral microbiota in alveolar bone homeostasis

X Cheng, X Zhou, C Liu, X Xu - Frontiers in Cellular and Infection …, 2021 - frontiersin.org
Osteomicrobiology is a new research field in which the aim is to explore the role of
microbiota in bone homeostasis. The alveolar bone is that part of the maxilla and mandible …

METTL3 regulates osteoblast differentiation and inflammatory response via Smad signaling and MAPK signaling

Y Zhang, X Gu, DI Li, L Cai, Q Xu - International Journal of Molecular …, 2019 - mdpi.com
Osteoblasts are crucial bone-building cells that maintain bone homeostasis, whereas
inflammatory stimuli can inhibit osteogenesis and activate inflammatory response. N6 …

[HTML][HTML] 3D printing of lithium osteogenic bioactive composite scaffold for enhanced bone regeneration

W Wang, J Wei, D Lei, S Wang, B Zhang… - Composites Part B …, 2023 - Elsevier
The repair of large bone defects is still a challenge in clinical orthopedics. The combination
of composite materials and 3D printing is expected to produce ideal bone defect scaffolds …

Anti-tumor effects of triptolide on angiogenesis and cell apoptosis in osteosarcoma cells by inducing autophagy via repressing Wnt/β-Catenin signaling

X Li, Q Lu, W Xie, Y Wang, G Wang - Biochemical and biophysical research …, 2018 - Elsevier
Osteosarcoma is a common malignant bone tumor occurring in adolescents and children.
The poor prognosis and low 5-year survival rate of osteosarcoma partly due to high …

High-fat diet/low-dose streptozotocin-induced type 2 diabetes in rats impacts osteogenesis and Wnt signaling in bone marrow stromal cells

C Qian, C Zhu, W Yu, X Jiang, F Zhang - PLoS One, 2015 - journals.plos.org
Bone regeneration disorders are a significant problem in patients with type 2 diabetes
mellitus. Bone marrow stromal cells (BMSCs) are recognized as ideal seed cells for tissue …

Lithium and Copper Induce the Osteogenesis‐Angiogenesis Coupling of Bone Marrow Mesenchymal Stem Cells via Crosstalk between Canonical Wnt and HIF‐1α …

Z Tan, B Zhou, J Zheng, Y Huang, H Zeng… - Stem Cells …, 2021 - Wiley Online Library
The combination of osteogenesis and angiogenesis dual‐delivery trace element‐carrying
bioactive scaffolds and stem cells is a promising method for bone regeneration and repair …

Baicalein enhances the osteogenic differentiation of human periodontal ligament cells by activating the Wnt/β-catenin signaling pathway

LJ Chen, BB Hu, XL Shi, MM Ren, WB Yu, SD Cen… - Archives of Oral …, 2017 - Elsevier
Objective Periodontium regeneration is one of the most important processes for periodontitis
therapy. Human periodontal ligament cells (hPDLCs) play a vital role in the repair and …

Wnt5a is involved in LOX‐1 and TLR4 induced host inflammatory response in peri‐implantitis

Q Zhang, J Liu, L Ma, N Bai, H Xu - Journal of periodontal …, 2020 - Wiley Online Library
Background and objective Peri‐implantitis is a plaque‐associated pathological condition
occurring in tissues around dental implants, characterized by inflammation in the peri …

Dietary isoquercetin ameliorates bone loss via restoration of the gut microbiota and lipopolysaccharide-triggered inflammatory status in ovariectomy mice

M Wu, C Chen, H Lei, Z Cao, C Zhang… - Journal of Agricultural …, 2023 - ACS Publications
Osteoporosis is one of the skeletal degenerative diseases accompanied by bone loss and
microstructure disruption. Given that the gut–bone signaling axis highly contributes to bone …