Decoding polygenic diseases: advances in noncoding variant prioritization and validation
IM Chin, ZA Gardell, MR Corces - Trends in Cell Biology, 2024 - cell.com
Genome-wide association studies (GWASs) provide a key foundation for elucidating the
genetic underpinnings of common polygenic diseases. However, these studies have …
genetic underpinnings of common polygenic diseases. However, these studies have …
Decoding biology with massively parallel reporter assays and machine learning
Massively parallel reporter assays (MPRAs) are powerful tools for quantifying the impacts of
sequence variation on gene expression. Reading out molecular phenotypes with …
sequence variation on gene expression. Reading out molecular phenotypes with …
MPRAVarDB: an online database and web server for exploring regulatory effects of genetic variants
Massively parallel reporter assay (MPRA) is an important technology for evaluating the
impact of genetic variants on gene regulation. Here, we present MPRAVarDB, an online …
impact of genetic variants on gene regulation. Here, we present MPRAVarDB, an online …
[HTML][HTML] MPRAVarDB: an online database and web server for exploring regulatory effects of genetic variants
J Nizomov, W Jin, Y Xia, Y Liu, Z Li, L Chen - bioRxiv, 2024 - ncbi.nlm.nih.gov
Massively parallel reporter assay (MPRA) is an important technology to evaluate the impact
of genetic variants on gene regulation. Here, we present MPRAVarDB, an online database …
of genetic variants on gene regulation. Here, we present MPRAVarDB, an online database …
MPRAVarDB: an online database and web server for exploring regulatory effects of genetic variants
Massively parallel reporter assay (MPRA) is an important technology to evaluate the impact
of genetic variants on gene regulation. Here, we present MPRAVarDB, an online database …
of genetic variants on gene regulation. Here, we present MPRAVarDB, an online database …