In the tissue engineering (TE) paradigm, engineering and life sciences tools are combined
to develop bioartificial substitutes for organs and tissues, which can in turn be applied in …

Current tissue regenerative strategies rely mainly on tissue repair by transplantation of the
synthetic/natural implants. However, limitations of the existing strategies have increased the …

The demonstrated ability to differentiate both human embryonic stem cells (hESCs) and
patient-derived induced pluripotent stem cells (hiPSCs) into hepatocyte-like cells (HLCs) …

Cellular therapies for liver diseases and in vitro models for drug testing both require
functional human hepatocytes (Hum-H), which have unfortunately been limited due to the …

Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) have the capacity
to differentiate into any specialized cell type of the human body, and therefore, ESC/iPSC …

Background Hepatic cell therapy has become a viable alternative to liver transplantation for
life-threatening liver diseases. However, the supply of human hepatocytes is limited due to …

The breath figure (BF) method is an easy, low-cost method to prepare films with a highly
organized honeycomb-like porous surface. The particular surface topography and porous …

Abstract The National Academy of Sciences publication, Toxicity Testing in the 21st Century:
A Vision and a Strategy, proposes a paradigm shift in toxicology from current animal-based …

Both human pluripotent stem cells (hPSCs) from embryonic stem cells (hESCs) and induced
pluripotent stem cells (hiPSCs) have the potential ability to differentiate into many different …

Mesenchymal stem cell (MSC)-based liver tissue engineering on nanofibrous scaffold holds
great promise for cell-based therapy in liver injuries and end-stage liver failure treatments …