The role of epigenetics in childhood autoimmune diseases with hematological manifestations

A Gkoutsias, A Makis - Pediatric Investigation, 2022 - mednexus.org
Autoimmune diseases with hematological manifestations are often characterized by
chronicity and relapses despite treatment, and the underlying pathogenetic mechanisms …

Translating mechanisms into therapeutic strategies for immune thrombocytopenia (ITP): Lessons from clinical trials

M Delshad, Z Davoodi-Moghaddam… - Thrombosis …, 2024 - Elsevier
Immune thrombocytopenia (ITP) is an autoimmune disorder that causes a significant
reduction in peripheral blood platelet count. Fortunately, due to an increased understanding …

DNMT3A-related overgrowth syndrome presenting with immune thrombocytopenic purpura

A Sezer, ÖK Güneş, B Kurucu - Current Research in Translational Medicine, 2025 - Elsevier
Abstract Tatton-Brown-Rahman syndrome (TBRS) is characterized by overgrowth, cognitive
deficiency, and distinctive facial features resulting from germline DNMT3A variants. This …

[HTML][HTML] Immune Thrombocytopenia: Immune Dysregulation and Genetic Perturbations Deciphering the Fate of Platelets

Z Tariq, MI Qadeer, K Zahid, EV Cherepkova… - Frontiers in Bioscience …, 2024 - imrpress.com
Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder. It involves impaired
production and excessive destruction of platelets. It is a complex and heterogeneous …