Surface modification of lipid-based nanoparticles
There is a growing interest in the development of lipid-based nanocarriers for multiple
purposes, including the recent increase of these nanocarriers as vaccine components …
purposes, including the recent increase of these nanocarriers as vaccine components …
PEGylation for enhancing nanoparticle diffusion in mucus
JT Huckaby, SK Lai - Advanced drug delivery reviews, 2018 - Elsevier
The viscoelastic mucus secretions coating exposed organs such as the lung airways and the
female reproductive tract can trap and quickly eliminate not only foreign pathogens and …
female reproductive tract can trap and quickly eliminate not only foreign pathogens and …
Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues
Mucus is a viscoelastic and adhesive gel that protects the lung airways, gastrointestinal (GI)
tract, vagina, eye and other mucosal surfaces. Most foreign particulates, including …
tract, vagina, eye and other mucosal surfaces. Most foreign particulates, including …
Cystic fibrosis: a mucosal immunodeficiency syndrome
TS Cohen, A Prince - Nature medicine, 2012 - nature.com
Cystic fibrosis transmembrane conductance regulator (CFTR) functions as a channel that
regulates the transport of ions and the movement of water across the epithelial barrier …
regulates the transport of ions and the movement of water across the epithelial barrier …
Toxicity of cellulose nanocrystals: a review
M Roman - Industrial Biotechnology, 2015 - liebertpub.com
Cellulose nanocrystals (CNCs) are a biobased nanomaterial attracting increasing interest
for a range of potential applications. This article reviews the current literature on the …
for a range of potential applications. This article reviews the current literature on the …
Pathophysiology and management of pulmonary infections in cystic fibrosis
RL Gibson, JL Burns, BW Ramsey - American journal of respiratory …, 2003 - atsjournals.org
This comprehensive State of the Art review summarizes the current published knowledge
base regarding the pathophysiology and microbiology of pulmonary disease in cystic …
base regarding the pathophysiology and microbiology of pulmonary disease in cystic …
Nutritional Cues Control Pseudomonas aeruginosa Multicellular Behavior in Cystic Fibrosis Sputum
KL Palmer, LM Aye, M Whiteley - Journal of bacteriology, 2007 - Am Soc Microbiol
The sputum (mucus) layer of the cystic fibrosis (CF) lung is a complex substrate that provides
Pseudomonas aeruginosa with carbon and energy to support high-density growth during …
Pseudomonas aeruginosa with carbon and energy to support high-density growth during …
Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice
Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene result in
defective epithelial cAMP-dependent Cl− secretion and increased airway Na+ absorption …
defective epithelial cAMP-dependent Cl− secretion and increased airway Na+ absorption …
Airway acidification initiates host defense abnormalities in cystic fibrosis mice
Cystic fibrosis (CF) is caused by mutations in the gene that encodes the cystic fibrosis
transmembrane conductance regulator (CFTR) anion channel. In humans and pigs, the loss …
transmembrane conductance regulator (CFTR) anion channel. In humans and pigs, the loss …
N-acylhomoserine lactones undergo lactonolysis in a pH-, temperature-, and acyl chain length-dependent manner during growth of Yersinia pseudotuberculosis and …
EA Yates, B Philipp, C Buckley, S Atkinson… - Infection and …, 2002 - Am Soc Microbiol
In gram-negative bacterial pathogens, such as Pseudomonas aeruginosa and Yersinia
pseudotuberculosis, cell-to-cell communication via the N-acylhomoserine lactone (AHL) …
pseudotuberculosis, cell-to-cell communication via the N-acylhomoserine lactone (AHL) …