More than two hundred papers have reported genome-wide data from ancient humans.
While the raw data for the vast majority are fully publicly available testifying to the …

Familial dysautonomia (FD) is an autosomal recessive hereditary sensory and autonomic
neuropathy (HSAN, type 3) expressed at birth with profound sensory loss and early death …

The availability of a large number of high‐density markers (SNPs) allows the estimation of
historical effective population size (N e) from linkage disequilibrium between loci. A recent …

The increasing availability of ancient DNA (aDNA) from human groups across space and
time has yielded deep insights into the movements of our species. However, given the …

Abstract The Linearbandkeramik (LBK) Neolithic communities were the first to spread
farming across large parts of Europe. We report genome-wide data for 250 individuals: 178 …

We present a method for detecting evidence of natural selection in ancient DNA time-series
data that leverages an opportunity not utilized in previous scans: testing for a consistent …

Abstract The LRRK2 G2019S variant is the most common cause of monogenic Parkinson's
disease (PD); however, questions remain regarding the penetrance, clinical phenotype and …

The risk of developing age-related macular degeneration (AMD) is influenced by genetic
background. In 2016, the International AMD Genomics Consortium (IAMDGC) identified 52 …

Quantitative and qualitative spermatogenic impairments are major causes of men's infertility.
Although in vitro fertilization (IVF) is effective, some couples persistently fail to conceive. To …

As an essential prerequisite to the genealogical study of Jews, some elements of Jewish
demographic history are provided in a long-term transnational perspective. Data and …