Purinergic signalling and cancer

G Burnstock, F Di Virgilio - Purinergic signalling, 2013 - Springer
Receptors for extracellular nucleotides are widely expressed by mammalian cells. They
mediate a large array of responses ranging from growth stimulation to apoptosis, from …

In-situ growth of boronic acid-decorated metal-organic framework on Fe3O4 nanospheres for specific enrichment of cis-diol containing nucleosides

S Feng, A Zhang, F Wu, X Luo, J Zhang - Analytica Chimica Acta, 2022 - Elsevier
In this study, a novel core-shell structured magnetic metal-organic framework nanospheres
(Fe 3 O 4@ PD@ BA-Zr-MOF) were fabricated by in-situ growth of boronic acid-decorated …

Platelets isolation and ectonucleotidase assay: Revealing functional aspects of the communication between the vasculature and the immune system

J Stabile, CR Fürstenau - Journal of Immunological Methods, 2024 - Elsevier
Platelets are enucleated fragments of cells with a diversity of internal granules. They are
responsible for functions related to hemostasis, coagulation, and inflammation. The …

Boronic acid-decorated metal-organic frameworks modified via a mixed-ligand strategy for the selective enrichment of cis-diol containing nucleosides

R Zhang, Z Wang, T Wang, P Su, Y Yang - Analytica Chimica Acta, 2020 - Elsevier
Functional metal–organic frameworks (MOFs) constructed via a pre-installation strategy of
introducing mixed organic ligands have attracted considerable interest in various fields. In …

Neuroprotective effect of quercetin in ectoenzymes and acetylcholinesterase activities in cerebral cortex synaptosomes of cadmium-exposed rats

FH Abdalla, AM Cardoso, LB Pereira… - Molecular and cellular …, 2013 - Springer
This study investigated the effect of quercetin on nucleoside triphosphate
diphosphohydrolase (NTPDase), 5′-nucleotidase, adenosine deaminase (ADA), and …

Altered purinergic signaling in the tumor associated immunologic microenvironment in metastasized non-small-cell lung cancer

S Schmid, M Kübler, CK Ayata, Z Lazar, B Haager… - Lung Cancer, 2015 - Elsevier
Objectives Purines are well-known as intracellular sources for energy but they also act as
extracellular signaling molecules. In the recent years, there has been a growing interest in …

Hydrophilic interaction chromatography coupled to tandem mass spectrometry in the presence of hydrophilic ion-pairing reagents for the separation of nucleosides …

M Mateos-Vivas, E Rodríguez-Gonzalo… - … of chromatography A, 2015 - Elsevier
A fast and efficient method for the simultaneous separation of highly polar compounds, in
this case nucleosides and nucleotide mono-, di-and triphosphates, using hydrophilic …

ADA activity is decreased in lymphocytes from patients with advanced stage of lung cancer

D Zanini, LH Manfredi, LP Pelinson, VC Pimentel… - Medical Oncology, 2019 - Springer
Cigarette smoking is directly associated with lung cancer. Non-small cell lung carcinoma
(NSCLC) represents approximately 80% from all types of lung cancer. This latter is hard to …

Naringenin mitigates iron-induced anxiety-like behavioral impairment, mitochondrial dysfunctions, ectonucleotidases and acetylcholinesterase alteration activities in …

Y Chtourou, AB Slima, R Gdoura, H Fetoui - Neurochemical Research, 2015 - Springer
Studies demonstrated that the iron chelating antioxidant restores brain dysfunction induced
by iron toxicity in animals. Earlier, we found that iron overload-induced cerebral cortex …

The signaling effects of ATP on melanoma-like skin cancer

A Mânica, BSR Bonadiman, AM Cardoso, A Paiz… - Cellular …, 2019 - Elsevier
Melanoma is a type of skin cancer originated by the malignant transformation of
melanocytes. Increasing incidence and mortality require efforts focused on studies and …