Endothelial cells are located at the crucial interface between circulating blood and semi-
solid tissues and have many important roles in maintaining systemic physiological function …

Similar to previous pandemics, COVID-19 has been succeeded by well-documented post-
infectious sequelae, including chronic fatigue, cough, shortness of breath, myalgia, and …

Simple Summary CDK4/6 inhibitors (CDKis) are a first-line treatment for metastatic hormone-
receptor-positive breast cancer, but resistance frequently develops. One potential resistance …

As life expectancy continues to rise, age-related diseases are becoming more prevalent. For
example, proteinuric glomerular diseases typified by podocyte injury have worse outcomes …

As a leading cause of chronic kidney disease, diabetic kidney disease (DKD) involves
insidious but progressive impairments of renal tubules, and is associated with premature …

Objective We aimed to evaluate the prognostic performance of circulating Klotho in coronary
atherosclerotic disease (CAD), and to further explore the effect of Klotho on stress-mediated …

Life expectancy is increasing worldwide, and by 2050 the proportion of the world's
population over 65 years of age is estimated to surpass 1.5 billion. Kidney aging is …

Cellular senescence accumulates with age and has been shown to impact numerous
physiological and pathological processes, including immune function. The role of cellular …

Choline Supplementation Improves Cognitive Performance in Frail Hypertensive Patients: Novel
Insights on Endothelial Function from the INTERVENTIONIST Study Choline Supplementation …

Abstract CDK4/6 inhibitors (CDKI) have improved disease control in hormone receptor-
positive, HER2-negative metastatic breast cancer, but most patients still develop progressive …