Chromatin accessibility: biological functions, molecular mechanisms and therapeutic application

Y Chen, R Liang, Y Li, L Jiang, D Ma, Q Luo… - Signal Transduction and …, 2024 - nature.com
The dynamic regulation of chromatin accessibility is one of the prominent characteristics of
eukaryotic genome. The inaccessible regions are mainly located in heterochromatin, which …

Conserved transcription factors coordinate synaptic gene expression through repression

JA Kentro, G Singh, TM Pham, J Currie, S Khullar… - bioRxiv, 2024 - biorxiv.org
Chemical synapses are the primary sites of communication in the nervous system.
Synaptogenesis is a complex transcellular process involving hundreds of proteins that must …