Neglected tropical diseases

N Feasey, M Wansbrough-Jones… - British medical …, 2010 - academic.oup.com
Introduction The neglected tropical diseases (NTDs) are infectious diseases that principally
impact the world's poorest people. They have been neglected for decades, initially as part of …

Ecology and transmission of Buruli ulcer disease: a systematic review

RW Merritt, ED Walker, PLC Small… - PLoS neglected …, 2010 - journals.plos.org
Buruli ulcer is a neglected emerging disease that has recently been reported in some
countries as the second most frequent mycobacterial disease in humans after tuberculosis …

How to diagnose acute appendicitis: ultrasound first

G Mostbeck, EJ Adam, MB Nielsen, M Claudon… - Insights into …, 2016 - Springer
Acute appendicitis (AA) is a common abdominal emergency with a lifetime prevalence of
about 7%. As the clinical diagnosis of AA remains a challenge to emergency physicians and …

Mosquitoes provide a transmission route between possums and humans for Buruli ulcer in southeastern Australia

PT Mee, AH Buultjens, J Oliver, K Brown… - Nature …, 2024 - nature.com
Buruli ulcer, a chronic subcutaneous infection caused by Mycobacterium ulcerans, is
increasing in prevalence in southeastern Australia. Possums are a local wildlife reservoir for …

Comparative genomic and phylogeographic analysis of Mycobacterium leprae

M Monot, N Honoré, T Garnier, N Zidane, D Sherafi… - Nature …, 2009 - nature.com
Reductive evolution and massive pseudogene formation have shaped the 3.31-Mb genome
of Mycobacterium leprae, an unculturable obligate pathogen that causes leprosy in humans …

Antimicrobial treatment for early, limited Mycobacterium ulcerans infection: a randomised controlled trial

WA Nienhuis, Y Stienstra, WA Thompson, PC Awuah… - The Lancet, 2010 - thelancet.com
Background Surgical debridement was the standard treatment for Mycobacterium ulcerans
infection (Buruli ulcer disease) until WHO issued provisional guidelines in 2004 …

A Major Role for Mammals in the Ecology of Mycobacterium ulcerans

JAM Fyfe, CJ Lavender, KA Handasyde… - PLoS neglected …, 2010 - journals.plos.org
Background Mycobacterium ulcerans is the causative agent of Buruli ulcer (BU), a
destructive skin disease found predominantly in sub-Saharan Africa and south-eastern …

Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans

C Demangel, TP Stinear, ST Cole - Nature Reviews Microbiology, 2009 - nature.com
Buruli ulcer is an emerging human disease caused by infection with a slow-growing
pathogen, Mycobacterium ulcerans, that produces mycolactone, a cytotoxin with …

Buruli ulcer: a review of the current knowledge

RR Yotsu, K Suzuki, RE Simmonds, R Bedimo… - … tropical medicine reports, 2018 - Springer
Abstract Purpose of the Review Buruli ulcer (BU) is a necrotizing and disabling cutaneous
disease caused by Mycobacterium ulcerans, one of the skin-related neglected tropical …

Macaque models of human infectious disease

MB Gardner, PA Luciw - ILAR journal, 2008 - academic.oup.com
Macaques have served as models for more than 70 human infectious diseases of diverse
etiologies, including a multitude of agents—bacteria, viruses, fungi, parasites, prions. The …