Metabolomics as a powerful tool for diagnostic, pronostic and drug intervention analysis in COVID-19
C Bruzzone, R Conde, N Embade, JM Mato… - Frontiers in Molecular …, 2023 - frontiersin.org
COVID-19 currently represents one of the major health challenges worldwide. Albeit its
infectious character, with onset affectation mainly at the respiratory track, it is clear that the …
infectious character, with onset affectation mainly at the respiratory track, it is clear that the …
[HTML][HTML] Systematic review with meta-analysis of diagnostic test accuracy for COVID-19 by mass spectrometry
Background The global COVID-19 pandemic has led to extensive development in many
fields, including the diagnosis of COVID-19 infection by mass spectrometry. The aim of this …
fields, including the diagnosis of COVID-19 infection by mass spectrometry. The aim of this …
Untargeted lipidomics reveals specific lipid profiles in COVID-19 patients with different severity from Campania region (Italy)
M Ciccarelli, F Merciai, A Carrizzo, E Sommella… - … of Pharmaceutical and …, 2022 - Elsevier
COVID-19 infection evokes various systemic alterations that push patients not only towards
severe acute respiratory syndrome but causes an important metabolic dysregulation with …
severe acute respiratory syndrome but causes an important metabolic dysregulation with …
Integrative plasma metabolic and lipidomic modelling of SARS-CoV-2 infection in relation to clinical severity and early mortality prediction
An integrative multi-modal metabolic phenotyping model was developed to assess the
systemic plasma sequelae of SARS-CoV-2 (rRT-PCR positive) induced COVID-19 disease …
systemic plasma sequelae of SARS-CoV-2 (rRT-PCR positive) induced COVID-19 disease …
Comprehensive lipidomic workflow for multicohort population phenotyping using stable isotope dilution targeted liquid chromatography-mass spectrometry
MJ Ryan, A Grant-St James, NG Lawler… - Journal of proteome …, 2023 - ACS Publications
Dysregulated lipid metabolism underpins many chronic diseases including cardiometabolic
diseases. Mass spectrometry-based lipidomics is an important tool for understanding …
diseases. Mass spectrometry-based lipidomics is an important tool for understanding …
[HTML][HTML] Quantitative serum NMR spectroscopy stratifies COVID-19 patients and sheds light on interfaces of host metabolism and the immune response with cytokines …
T Rössler, G Berezhnoy, Y Singh, C Cannet… - Metabolites, 2022 - mdpi.com
The complex manifestations of COVID-19 are still not fully decoded on the molecular level.
We combined quantitative the nuclear magnetic resonance (NMR) spectroscopy serum …
We combined quantitative the nuclear magnetic resonance (NMR) spectroscopy serum …
Dynamic modulations of sphingolipids and glycerophospholipids in COVID‐19
M Kurano, K Okamoto, D Jubishi… - Clinical and …, 2022 - Wiley Online Library
Background A heterogeneous clinical phenotype is a characteristic of coronavirus disease
2019 (COVID‐19). Therefore, investigating biomarkers associated with disease severity is …
2019 (COVID‐19). Therefore, investigating biomarkers associated with disease severity is …
J-edited DIffusional proton nuclear magnetic resonance spectroscopic measurement of glycoprotein and supramolecular phospholipid biomarkers of inflammation in …
P Nitschke, S Lodge, T Kimhofer, R Masuda… - Analytical …, 2022 - ACS Publications
Proton nuclear magnetic resonance (NMR) N-acetyl signals (Glyc) from glycoproteins and
supramolecular phospholipids composite peak (SPC) from phospholipid quaternary …
supramolecular phospholipids composite peak (SPC) from phospholipid quaternary …
Metabolomic profiling of plasma reveals differential disease severity markers in COVID-19 patients
LB Oliveira, VI Mwangi, MA Sartim, J Delafiori… - Frontiers in …, 2022 - frontiersin.org
The severity, disabilities, and lethality caused by the coronavirus 2019 (COVID-19) disease
have dumbfounded the entire world on an unprecedented scale. The multifactorial aspect of …
have dumbfounded the entire world on an unprecedented scale. The multifactorial aspect of …
Differential abundance of lipids and metabolites related to SARS-CoV-2 infection and susceptibility
OE Albóniga, E Moreno, J Martínez-Sanz, P Vizcarra… - Scientific Reports, 2023 - nature.com
The mechanisms driving SARS-CoV-2 susceptibility remain poorly understood, especially
the factors determining why unvaccinated individuals remain uninfected despite high-risk …
the factors determining why unvaccinated individuals remain uninfected despite high-risk …