[HTML][HTML] Epstein-Barr virus-encoded microRNAs as regulators in host immune responses

M Wang, F Yu, W Wu, Y Wang, H Ding… - International journal of …, 2018 - ncbi.nlm.nih.gov
Epstein-Barr virus (EBV) is an oncogenic virus that infects over 90% of the world's adult
population. EBV can establish life-long latent infection in host due to the balance between …

The biology of EBV infection in human epithelial cells

SW Tsao, CM Tsang, PS Pang, G Zhang… - Seminars in cancer …, 2012 - Elsevier
EBV-associated human malignancies may originate from B cells and epithelial cells. EBV
readily infects B cells in vitro and transforms them into proliferative lymphoblastoid cell lines …

Efficient replication of Epstein–Barr virus in stratified epithelium in vitro

RM Temple, J Zhu, L Budgeon… - Proceedings of the …, 2014 - National Acad Sciences
Epstein–Barr virus is a ubiquitous human herpesvirus associated with epithelial and
lymphoid tumors. EBV is transmitted between human hosts in saliva and must cross the oral …

Conserved herpesvirus kinases target the DNA damage response pathway and TIP60 histone acetyltransferase to promote virus replication

R Li, J Zhu, Z Xie, G Liao, J Liu, MR Chen, S Hu… - Cell host & …, 2011 - cell.com
Herpesviruses, which are major human pathogens, establish life-long persistent infections.
Although the α, β, and γ herpesviruses infect different tissues and cause distinct diseases …

Virus and cell RNAs expressed during Epstein-Barr virus replication

J Yuan, E Cahir-McFarland, B Zhao, E Kieff - Journal of virology, 2006 - Am Soc Microbiol
ABSTRACT Changes in Epstein-Barr virus (EBV) and cell RNA levels were assayed
following immunoglobulin G (IgG) cross-linking-induced replication in latency 1-infected …

Functions of the Epstein-Barr virus EBNA1 protein in viral reactivation and lytic infection

N Sivachandran, X Wang, L Frappier - Journal of virology, 2012 - Am Soc Microbiol
ABSTRACT EBNA1 is the only nuclear Epstein-Barr virus (EBV) protein expressed in both
latent and lytic modes of infection. While EBNA1 is known to play several important roles in …

Epstein-Barr virus perpetuates B cell germinal center dynamics and generation of autoimmune-associated phenotypes in vitro

ED SoRelle, NM Reinoso-Vizcaino, GQ Horn… - Frontiers in …, 2022 - frontiersin.org
Human B cells encompass functionally diverse lineages and phenotypic states that
contribute to protective as well as pathogenic responses. Epstein-Barr virus (EBV) provides …

Differential B‐lymphocyte regulation by CD40 and its viral mimic, latent membrane protein 1

JP Graham, KM Arcipowski… - Immunological reviews, 2010 - Wiley Online Library
CD40 plays a vital role in humoral immunity, via its potent and multifaceted function as an
activating receptor of various immune cells, most notably B lymphocytes. The Epstein‐Barr …

Epstein–Barr virus and risk of breast cancer: a systematic review and meta-analysis

M Farahmand, SH Monavari, Z Shoja, H Ghaffari… - Future …, 2019 - Taylor & Francis
Despite the numerous publications regarding the role of Epstein–Barr virus (EBV) in breast
cancer development, the topic has still remained controversial. The aim of the meta-analysis …

[HTML][HTML] Epstein-Barr virus: Current questions and challenges

L Frappier - Tumour Virus Research, 2021 - Elsevier
Epstein-Barr virus (EBV) infects most people worldwide and persists for life due to
complicated interplay between lytic infection and multiple types of latent infections. While …