Adeno-associated virus (AAV) vector-mediated gene delivery was recently approved for the
treatment of inherited blindness and spinal muscular atrophy, and long-term therapeutic …

The adeno-associated virus (AAV) is a small, nonpathogenic parvovirus, which depends on
helper factors to replicate. Those helper factors can be provided by coinfecting helper …

Recombinant gene delivery vectors derived from naturally occurring or genetically
engineered adeno-associated viruses (AAV) have taken center stage in human gene …

Discovered as a contaminant of adenovirus stocks in the 1960s, adeno-associated virus
(AAV) is a mono-stranded DNA virus that depends on helper factors to replicate. Even …

Adeno-associated virus (AAV) belongs to the Dependoparvovirus genus of the Parvoviridae
family. AAV replication relies on a helper virus, such as adenovirus (Ad). Co-infection of AAV …

Several viruses target the human respiratory tract, causing different clinical manifestations
spanning from mild upper airway involvement to life-threatening acute respiratory distress …

Viral infection is still a serious global health problem that kills hundreds of thousands of
people annually. Understanding the mechanism by which virus replicates, packages, and …

The last decade has been marked by two eminent discoveries that have changed our
perception of the virology field: The discovery of giant viruses and a distinct new class of …

Recombinant adeno-associated viruses (rAAVs) stand at the forefront of gene therapy
applications, holding immense significance for their safe and efficient gene delivery …

Introduction: Cystic fibrosis (CF) remains a life-threatening genetic disease, with few
clinically effective treatment options. Gene therapy and gene editing strategies offer the …