Haemostasis stops bleeding at the site of vascular injury and maintains the integrity of blood
vessels through clot formation. This regulated physiological process consists of complex …

Platelets have been hypothesized to promote certain neoplastic malignancies; however,
antiplatelet drugs are still not part of routine pharmacological cancer prevention and …

Systemic antiplatelet treatment represents a promising option to improve the therapeutic
outcomes and therapeutic efficacy of chemotherapy and immunotherapy due to the critical …

Simple Summary Almost all cell types produce extracellular vesicles that, according to their
size, subcellular origin and release pathways, are mainly categorized as exosomes …

Tumor cells have the ability to induce platelet activation and aggregation. This has been
documented to be involved in tumor progression in several types of cancers, such as lung …

Background In addition to their pivotal roles in coagulation and thrombosis, platelets are
crucial in tumor progression, with plenty of clinical and experimental data demonstrating that …

Platelet function can be modified by cancer cells to support tumor growth, causing
alterations in the delicate hemostatic equilibrium. Cancer-cell and platelet interactions are …

Platelet-derived large extracellular vesicles (often referred to as microparticles in the field of
cardiovascular disease) have been identified as effector in the atherothrombotic process …

Spontaneous venous thrombosis is often the first clinical sign of cancer, and it is linked to a
worsened survival rate. Traditionally, tumor-cell induced platelet activation has been the …

Platelets play a critical role in hemostasis and thrombus formation. Platelets are small,
anucleate, and short-lived blood cells that are produced by the large, polyploid, and …