The respiratory response to hypoxia in mammals develops from an inhibition of breathing
movements in utero into a sustained increase in ventilation in the adult. This ventilatory …

Peripheral chemoreceptors and cardiovascular regulation Page 1 PHYSIOLOGICAL
REVIEWS Vol. 74, No. 3, July 1994 Printed in USA Peripheral Chemoreceptors and …

Development of the mammalian respiratory control system begins early in gestation and
does not achieve mature form until weeks or months after birth. A relatively long gestation …

Respiratory Physiology of Newborn Mammals: A Comparative Perspective emphasizes
common trends among mammalian species in an effort to extract general rules about both …

The past decade has witnessed rapid progress in defining neural circuits and mechanisms
in the brain, responsible for regulation of the sympathetic nerve activity and cardiovascular …

Selected topics in the respiratory response to acute hypoxia in the fetus and newborn are
reviewed. Peripheral chemoreceptors acting through ionotrophic glutamate receptors play …

1. The effect of PCO2 upon the discharge response to changes in PO2 (between ca 450 and
30 mmHg) was observed in adult (> 5 weeks old) and neonatal (5‐7 days old) rat carotid …

Any general model of respiratory control must explain a puzzling array of breathing patterns
that are observed during the course of a lifetime. Particular challenges are to understand …

We studied respiratory functions in mutant mice deficient in endothelin-1 (ET-1) generated
by gene targeting. In conscious adult mice heterozygous for ET-1 gene mutation (ET+ …

Our goal was to describe the in situ responses in rats of single-unit carotid body
chemoreceptors to changes in arterial PO 2 and P CO 2. We identified single-unit carotid …