Fibrosis is the formation of fibrous connective tissue in response to injury. It is characterized
by the accumulation of extracellular matrix components, particularly collagen, at the site of …

Stem cells play an important role in restoring cardiac function in the damaged heart. In order
to mediate repair, stem cells need to replace injured tissue by differentiating into specialized …

Aging leads to increased cellular senescence and is associated with decreased potency of
tissue‐specific stem/progenitor cells. Here, we have done an extensive analysis of cardiac …

The epidemic of heart failure has stimulated interest in understanding cardiac regeneration.
Evidence has been reported supporting regeneration via transplantation of multiple cell …

Exercise training fosters the health and performance of the cardiovascular system, and
represents nowadays a powerful tool for cardiovascular therapy. Exercise exerts its …

Objectives: The purpose of this study was to test the ability of insulin-like growth factor (IGF)-
1/hepatocyte growth factor (HGF) to activate resident endogenous porcine cardiac …

Aims It is a dogma of cardiovascular pathophysiology that the increased cardiac mass in
response to increased workload is produced by the hypertrophy of the pre-existing …

A highly heterogeneous population of stem and progenitor cells has been described by light
immunohistochemistry in the mammalian adult heart, but the ultrastructural identity of …

A hyperadrenergic state is a seminal aspect of chronic heart failure. Also," Takotsubo stress
cardiomyopathy," is associated with increased plasma catecholamine levels. The …

Activation of endogenous cardiac stem/progenitor cells (eCSCs) can improve cardiac repair
after acute myocardial infarction. We studied whether the in situ activation of eCSCs by …