Fibrotic scar in CNS injuries: from the cellular origins of fibroblasts to the molecular processes of fibrotic scar formation
Central nervous system (CNS) trauma activates a persistent repair response that leads to
fibrotic scar formation within the lesion. This scarring is similar to other organ fibrosis in …
fibrotic scar formation within the lesion. This scarring is similar to other organ fibrosis in …
The secretome of macrophages has a differential impact on spinal cord injury recovery according to the polarization protocol
J Lentilhas-Graça, DJ Santos, J Afonso… - Frontiers in …, 2024 - frontiersin.org
Introduction The inflammatory response after spinal cord injury (SCI) is an important
contributor to secondary damage. Infiltrating macrophages can acquire a spectrum of …
contributor to secondary damage. Infiltrating macrophages can acquire a spectrum of …
Myelin‐associated glycoprotein alters the neuronal secretome and stimulates the release of TGFβ and proteins that affect neural plasticity
VD Stewart, J Cadieux, MR Thulasiram… - FEBS …, 2022 - Wiley Online Library
Myelin‐associated glycoprotein (MAG) and Nogo inhibit neurite outgrowth by binding to
receptors such as NgR1, PirB and LRP1, and they have also been shown to induce …
receptors such as NgR1, PirB and LRP1, and they have also been shown to induce …
Serum microRNA as a potential biomarker for the activity of thyroid eye disease
N Kim, H Choung, YJ Kim, SE Woo, MK Yang… - Scientific Reports, 2023 - nature.com
The aim of this study is to characterize the microRNA (miRNA) expression signatures in
patients with thyroid eye disease (TED) and identify miRNA biomarkers of disease activity …
patients with thyroid eye disease (TED) and identify miRNA biomarkers of disease activity …
Amphiregulin and growth differentiation factor 11 promote retinal ganglion cell survival in vivo through activation of Smad3
HS Yoo - 2022 - repository.library.carleton.ca
Although adult neurons in the mammalian central nervous system do not spontaneously
regenerate after injury, growing evidence indicates that genetically manipulating them can …
regenerate after injury, growing evidence indicates that genetically manipulating them can …