Directed evolution of stereo‐, regio‐, and chemoselective enzymes constitutes a unique way
to generate biocatalysts for synthetically interesting transformations in organic chemistry and …

Nitrile hydratase (NHase, EC 4.2. 1.84) is one type of metalloenzyme participating in the
biotransformation of nitriles into amides. Given its catalytic specificity in amide production …

Abstract Nitrile hydratase (NHase; EC 4.2. 1.84) is widely used to synthesize the
corresponding amides from nitriles, which is the most successful green biocatalyst …

Cinnamamide and its derivatives are the most common and important building blocks widely
present in natural products. Currently, nitrile hydratase (NHase, EC 4.2. 1.84) has been …

Acrylamide is an important bulk chemical used for producing polyacrylamide, which is
widely applied in diverse fields, such as enhanced oil recovery and water treatment …

High thermostability and catalytic activity are key properties for nitrile hydratase (NHase, EC
4.2. 1.84) as a well-industrialized catalyst. In this study, rational design was applied to tailor …

Nitrile hydratase (NHase) is able to bio-transform nitriles into amides. As nitrile hydration
being an exothermic reaction, a NHase with high activity and stability is needed for amide …

Die gerichtete Evolution von stereo‐, regio‐und chemoselektiven Enzymen ist ein
einzigartiges Verfahren zur Herstellung von Biokatalysatoren für synthetisch interessante …

The aromatic substrate profile of the cobalt nitrile hydratase from Rhodococcus rhodochrous
ATCC BAA 870 was evaluated against a wide range of nitrile containing compounds (> 60) …

Nicotinamide is a high‐value chemical that has been widely applied in various aspects of
daily life. Nitrile hydratase (NHase) is capable of carrying out biotransformation of nitriles to …