Abstract Corona virus disease 2019 (COVID‐19) causes symptoms from multiple organs
after infection by severe acute respiratory syndrome corona virus 2 (SARS CoV‐2). They …

The effectiveness of anticancer drugs in treating a solid tumour is dependent on delivery of
the drug to virtually all cancer cells in the tumour. The distribution of drug in tumour tissue …

Physical forces have a crucial role in tumor progression and cancer treatment. The
application of principles of engineering and physical sciences to oncology has provided …

Tumors generate physical forces during growth and progression. These physical forces are
able to compress blood and lymphatic vessels, reducing perfusion rates and creating …

First identified in 1974, m 6 A RNA methylation, which serves as a predominant internal
modification of RNA in higher eukaryotes, has gained prodigious interest in recent years …

Blood vessels deliver oxygen and nutrients to every part of the body, but also nourish
diseases such as cancer. Over the past decade, our understanding of the molecular …

Despite having an abundant number of vessels, tumours are usually hypoxic and nutrient-
deprived because their vessels malfunction. Such abnormal milieu can fuel disease …

New vessel formation (angiogenesis) is an essential physiological process for embryologic
development, normal growth, and tissue repair. Angiogenesis is tightly regulated at the …

Blood perfusion in tumors can be significantly lower than that in the surrounding normal
tissue owing to the leakiness and/or compression of tumor blood vessels. Impaired perfusion …

Extracellular microparticles (MPs) can function as drug-delivery vehicles for anticancer
drugs. Here, we show that the softness of MPs derived from tumour-repopulating cells …