Streptococcus pyogenes (Group A Streptococcus; GAS) is an exclusively human pathogen.
This bacterial species is responsible for a large variety of infections, ranging from purulent …

The Alphaproteobacteria uniquely integrate features of two-component signal transduction
and alternative σ factor regulation to control transcription of genes that ensure growth and …

The arginine deiminase (ADI) pathway has been found in many kinds of bacteria and
functions to supplement energy production and provide protection against acid stress. The …

The c ontrol ofv irulence gene r egulator (CovR), also called c aspsule s ynthesis r egulator
(CsrR), is critical to how the major human pathogen group A Streptococcus fine-tunes …

The control of virulence regulator/sensor kinase (CovRS) two-component system is critical to
the infectivity of group A streptococcus (GAS), and CovRS inactivating mutations are …

Many bacterial pathogens coordinately regulate genes encoding important metabolic
pathways during disease progression, including the phosphoenolpyruvate (PEP) …

Adaptation of group A Streptococcus (GAS) to its human host is mediated by two-component
systems that transduce external stimuli to regulate bacterial physiology. Among such …

Phenotypic heterogeneity is commonly observed between isolates of a given pathogen.
Epidemiological analyses have identified that some serotypes of the group AS treptococcus …

Necrotizing fasciitis is a severe infectious disease that results in significant mortality.
Streptococcus pyogenes (group A Streptococcus, GAS) is one of the most common bacterial …

Streptococcus pyogenes, also known as group A Streptococcus, causes a wide variety of
diseases ranging from mild noninvasive to severe invasive infections. To identify possible …