Asthma is a heterogenous disease characterized by multiple phenotypes driven by different
mechanisms. The implementation of precision medicine in the management of asthma …

The potential of precision medicine in allergy and asthma has only started to be explored. A
significant clarification in the pathophysiology of rhinitis, chronic rhinosinusitis, asthma, food …

Severe asthma is heterogeneous in its clinical presentation, underlying pathophysiology,
course and response to therapy. Clinical and physiological assessment of severe asthma is …

Abstract Purpose of Review Asthma is a heterogeneous disease characterized by multiple
phenotypes. Treatment of patients with severe disease can be challenging. Predictive …

This review summarizes some of the most significant advances in asthma research over the
past year. We first focus on novel discoveries in the mechanism of asthma development and …

Bronchial asthma is a heterogeneous disease with complex pathological mechanisms
representing different phenotypes, including severe asthma. The airway epithelium is a …

Background Asthma is a disease that can be separated into different phenotypes and
endotypes based on the clinical characteristics and the molecular mechanisms of the …

Asthma is a complex disease with a variable course. Efforts to identify biomarkers to predict
asthma severity, the course of disease and response to treatment have not been very …

Type-2 airway inflammation is a major characteristic of asthma. Assessing its degree of
severity is, therefore, essential in asthma management. Periostin, a matricellular protein …

Background Type 2 biomarkers that predict both likelihood of future severe exacerbations
and response to mAb therapy in asthma would be useful clinically in identifying patients both …