Extracellular matrix hydrogel therapies: In vivo applications and development

MT Spang, KL Christman - Acta biomaterialia, 2018 - Elsevier
Decellularized extracellular matrix (ECM) has been widely used for tissue engineering
applications and is becoming increasingly versatile as it can take many forms, including …

Small intestinal submucosa: superiority, limitations and solutions, and its potential to address bottlenecks in tissue repair

G Cao, Y Huang, K Li, Y Fan, H Xie, X Li - Journal of Materials …, 2019 - pubs.rsc.org
Over the past few decades, small intestinal submucosa (SIS), a naturally occurring
decellularized extracellular matrix (ECM), has attracted much attention in tissue repair …

Microsphere–Gel Composite System with Mesenchymal Stem Cell Recruitment, Antibacterial, and Immunomodulatory Properties Promote Bone Regeneration via …

S Ma, C Wang, Y Dong, W Jing, P Wei… - … Applied Materials & …, 2022 - ACS Publications
Various types of biomaterials have been widely used to treat complex bone defects.
However, potential infection risks and inappropriate host immune responses induced by …

Preparation and characterization of pro-angiogenic gel derived from small intestinal submucosa

W Wang, X Zhang, NN Chao, TW Qin, W Ding, Y Zhang… - Acta biomaterialia, 2016 - Elsevier
Gels derived from decellularized small intestinal submucosa (SIS) have been used to repair
ischemic myocardium and deliver protein drug. However, their material properties and …

Processed tissue–derived extracellular matrices: tailored platforms empowering diverse therapeutic applications

S Krishtul, L Baruch, M Machluf - Advanced Functional …, 2020 - Wiley Online Library
Tissue‐derived decellularized extracellular matrices (dECM) have gradually become the
gold standard of scaffolds for tissue engineering, owing to their close mirroring of the …

Hyaluronic acid/alginate hydrogel containing hepatocyte growth factor and promotion of vocal fold wound healing

JS Choi, S Heang Oh, YM Kim, JY Lim - Tissue Engineering and …, 2020 - Springer
Background: Hepatocyte growth factor (HGF) has been shown to facilitate vocal fold (VF)
wound healing. This study was undertaken to determine whether the therapeutic efficacy of …

ECM coating modification generated by optimized decellularization process improves functional behavior of BMSCs

M Li, T Zhang, J Jiang, Y Mao, A Zhang… - Materials Science and …, 2019 - Elsevier
Bone mesenchymal stem cells (BMSCs) have been widely applied in tissue engineering
and regenerative medicine. However, small number of BMSCs and loss of stem cell …

Controlled delivery of icariin on small intestine submucosa for bone tissue engineering

M Li, Q Gu, M Chen, C Zhang, S Chen… - Materials Science and …, 2017 - Elsevier
Small intestine submucosa (SIS) has been reported as an excellent biomaterial for tissue
engineering because of its naturally occurring collagenous extracellular matrix property with …

Modification of the small intestinal submucosa membrane with oligopeptides screened from intrinsically disordered regions to promote angiogenesis and accelerate …

S Ma, Y Yang, Y Mu, H Peng, P Wei, W Jing… - Biomaterials …, 2023 - Elsevier
A slow vascularization rate is considered one of the major disadvantages of biomaterials
used for accelerating wound healing. Several efforts, including cellular and acellular …

Grafting of mesenchymal stem cell-seeded small intestinal submucosa to repair the deep partial-thickness burns

X Guo, B Xia, XB Lu, ZJ Zhang, Z Li, WL Li… - Connective Tissue …, 2016 - Taylor & Francis
Purpose: Regenerative medicine provides many treatments for burn wounds, of which cell-
seeded substitutes are encouraging for large and deep burns. To assess the feasibility of …