Synaptic specificity, recognition molecules, and assembly of neural circuits
JR Sanes, SL Zipursky - Cell, 2020 - cell.com
Developing neurons connect in specific and stereotyped ways to form the complex circuits
that underlie brain function. By comparison to earlier steps in neural development, progress …
that underlie brain function. By comparison to earlier steps in neural development, progress …
Specification of synaptic connectivity by cell surface interactions
The molecular diversification of cell surface molecules has long been postulated to impart
specific surface identities on neuronal cell types. The existence of unique cell surface …
specific surface identities on neuronal cell types. The existence of unique cell surface …
Sour sensing from the tongue to the brain
The ability to sense sour provides an important sensory signal to prevent the ingestion of
unripe, spoiled, or fermented foods. Taste and somatosensory receptors in the oral cavity …
unripe, spoiled, or fermented foods. Taste and somatosensory receptors in the oral cavity …
Regulation of neural circuit formation by protocadherins
SL Peek, KM Mah, JA Weiner - Cellular and molecular life sciences, 2017 - Springer
The protocadherins (Pcdhs), which make up the most diverse group within the cadherin
superfamily, were first discovered in the early 1990s. Data implicating the Pcdhs, including …
superfamily, were first discovered in the early 1990s. Data implicating the Pcdhs, including …
Synapse development and maturation at the drosophila neuromuscular junction
VT Chou, SA Johnson, D Van Vactor - Neural development, 2020 - Springer
Synapses are the sites of neuron-to-neuron communication and form the basis of the neural
circuits that underlie all animal cognition and behavior. Chemical synapses are specialized …
circuits that underlie all animal cognition and behavior. Chemical synapses are specialized …
A subset of autism-associated genes regulate the structural stability of neurons
YC Lin, JA Frei, MBC Kilander, W Shen… - Frontiers in cellular …, 2016 - frontiersin.org
Autism spectrum disorder (ASD) comprises a range of neurological conditions that affect
individuals' ability to communicate and interact with others. People with ASD often exhibit …
individuals' ability to communicate and interact with others. People with ASD often exhibit …
Nitric Oxide-Scavenging, Anti-Migration Effects, and Glycosylation Changes after Hemin Treatment of Human Triple-Negative Breast Cancer Cells: A Mechanistic …
The enhanced expression of nitric oxide (• NO) synthase predicts triple-negative breast
cancer outcome and its resistance to different therapeutics. Our earlier work demonstrated …
cancer outcome and its resistance to different therapeutics. Our earlier work demonstrated …
CDH2 mutation affecting N-cadherin function causes attention-deficit hyperactivity disorder in humans and mice
Attention-deficit hyperactivity disorder (ADHD) is a common childhood-onset psychiatric
disorder characterized by inattention, impulsivity and hyperactivity. ADHD exhibits …
disorder characterized by inattention, impulsivity and hyperactivity. ADHD exhibits …
Flying under the radar: CDH2 (N-cadherin), an important hub molecule in neurodevelopmental and neurodegenerative diseases
ZI László, Z Lele - Frontiers in Neuroscience, 2022 - frontiersin.org
CDH2 belongs to the classic cadherin family of Ca2+-dependent cell adhesion molecules
with a meticulously described dual role in cell adhesion and β-catenin signaling. During …
with a meticulously described dual role in cell adhesion and β-catenin signaling. During …
Coordinated cadherin functions sculpt respiratory motor circuit connectivity
AN Vagnozzi, MT Moore, M Lin, EM Brozost, KC Ritesh… - Elife, 2022 - elifesciences.org
Breathing, and the motor circuits that control it, is essential for life. At the core of respiratory
circuits are Dbx1-derived interneurons, which generate the rhythm and pattern of breathing …
circuits are Dbx1-derived interneurons, which generate the rhythm and pattern of breathing …