Molecular tests for tuberculosis (TB) have the potential to help reach the three million people
with TB who are undiagnosed or not reported each year and to improve the quality of care …

Diagnosis of tuberculosis, and especially the diagnosis of extrapulmonary tuberculosis, still
faces challenges in clinical practice. There are several reasons for this. Methods based on …

Anaemia is a global public health concern, afflicting adolescent girls, women of reproductive
age, pregnant women and children in low-and middle-income countries. 1 Reduction of …

The clustered regularly interspaced short palindromic repeats (CRISPR) molecular system
has emerged as a promising technology for the detection of nucleic acids. Herein, the …

Next generation sequencing is in the process of evolving from a technology used for
research purposes to one which is applied in clinical diagnostics. Recently introduced high …

Rapid diagnosis is one key pillar to end tuberculosis (TB). Point-of-care tests (POCTs)
facilitate early detection, immediate treatment, and reduced transmission of TB disease. This …

Two billion people are infected with Mycobacterium tuberculosis, leading to 10 million new
cases of active tuberculosis and 1.5 million deaths annually. Universal access to drug …

Background Tuberculosis remains a global public health threat, and the development of
rapid and precise diagnostic tools is the key to enabling the early start of treatment …

The World Health Organization's End TB Strategy prioritizes universal access to an early
diagnosis and comprehensive drug susceptibility testing (DST) for all individuals with …

Drug-resistant tuberculosis is a substantial health-care concern worldwide. Despite culture-
based methods being considered the gold standard for drug susceptibility testing, molecular …