New Delhi metallo-β-lactamase (NDM) is a metallo-β-lactamase able to hydrolyze almost all
β-lactams. Twenty-four NDM variants have been identified in> 60 species of 11 bacterial …

Background Carbapenem resistance is defined as in vitro non-susceptibility to any
carbapenem and/or documented production of a carbapenemase. This feature has rapidly …

Background Antimicrobial resistance (AMR) poses an important global health challenge in
the 21st century. A previous study has quantified the global and regional burden of AMR for …

Background Infections due to antibiotic-resistant bacteria are threatening modern health
care. However, estimating their incidence, complications, and attributable mortality is …

Biofilms form a complex layer with defined structures, that attach on biotic or abiotic surfaces,
are tough to eradicate and tend to cause some resistance against most antibiotics. Several …

Abstract Carbapenem-resistant Enterobacteriaceae (CRE), Acinetobacter baumannii
(CRAB), and Pseudomonas aeruginosa (CRPsA) are a serious cause of healthcare …

Klebsiella species cause infections at multiple sites, including lung, urinary tract,
bloodstream, wound or surgical site, and brain. These infections are more likely to occur in …

The emergence of carbapenem-resistant Enterobacterales (CRE) has become a major
public health concern. Moreover, its colonization among residents of long-term care facilities …

Background Rates of colonization and infection with carbapenem-resistant Gram-negative
pathogens are on the rise, particularly in southeastern European countries, and this is …

The prevalence of Carbapenem-resistant Enterobacteriaceae (CRE) has increased
dramatically in recent years and has become a global public health issue. Since …