An important component of tissue engineering (TE) is the supporting matrix upon which cells
and tissues grow, also known as the scaffold. Scaffolds must easily integrate with host tissue …

Although great progress has been made in the isolation and culture of stem cells, the future
of stem-cell-based therapies and their productive use in drug discovery and regenerative …

Background Although human embryonic stem cells (hESCs) hold great promise as a source
of differentiated cells to treat several human diseases, many obstacles still need to be …

Background Heterogeneity of endothelial cells (ECs) is a hallmark of the vascular system
which may impact the development and management of vascular disorders. Despite the …

The purpose of this study was to determine whether a proprietary xeno-free synthetic culture
surface could be used to aid in the production and subsequent retinal-specific differentiation …

Aim: Human embryonic stem cells (hESCs) are able to self‐renew and differentiate into a
variety of cell types. Although miRNAs have emerged as key regulators in the cellular …

This review describes recent developments regarding the use of natural and synthetic
polymers to support the propagation of human pluripotent stem cells (hPSCs), human …

The protocols described here are comprehensive instructions for deriving human embryonic
stem (hES) cell lines in xeno-free conditions from cryopreserved embryos. Details are …

The boundaries of embryonic stem cell (ESC) research have extended considerably in
recent years in several important ways. Alongside a deeper understanding of the pluripotent …

To realize their potentials, embryonic stem (ES) cells must be maintained in optimal culture
conditions that preserve their pluripotency and self‐renewal capacity. Mouse embryonic …