Health professionals are encouraged to take the ESC Guidelines fully into account when
exercising their clinical judgment, as well as in the determination and the implementation of …

In this review, the authors reflect upon the role of coronary physiology in the modern
management of coronary artery disease. They critically appraise the scientific background of …

Background Coronary revascularization guided by fractional flow reserve (FFR) is
associated with better patient outcomes after the procedure than revascularization guided by …

Objectives: The aim of this study was to investigate the clinical outcomes of patients deferred
from coronary revascularization on the basis of instantaneous wave-free ratio (iFR) or …

Objectives: This study compared the diagnostic performance with adenosine-derived
fractional flow reserve (FFR)≤ 0.8 of contrast-based FFR (cFFR), resting distal pressure …

Ischemic heart disease is a dynamic process of atherosclerosis of the coronary arteries or
functional alterations of coronary circulation that can be modified by lifestyle …

Objectives: This work compares the diagnostic performance of adenosine-free coronary
pressure wire indices based on lesion location. Background: Several adenosine-free …

Aims The instantaneous wave-free ratio (iFR) and whole-cycle Pd/Pa investigate coronary
physiology during non-hyperaemic conditions. To test for unique physiologic properties of …

This review provides an integrative and forward-looking perspective on the gamut of
coronary physiology for the diagnosis and management of atherosclerosis. Because clinical …

Objectives: This study investigated the diagnostic performance of instantaneous wave-free
ratio (iFR) in patients with aortic valve stenosis (AS). Background: The iFR was introduced …