Parahydrogen-based NMR signal amplification by reversible exchange (SABRE): Recent advances and applications
OG Salnikov, DB Burueva, IV Skovpin… - Mendeleev …, 2023 - Elsevier
Signal amplification by reversible exchange (SABRE) is a rapidly developing nuclear
magnetic resonance (NMR) hyperpolarization technique utilizing parahydrogen for dramatic …
magnetic resonance (NMR) hyperpolarization technique utilizing parahydrogen for dramatic …
Parahydrogen‐Induced Hyperpolarization of Gases
KV Kovtunov, IV Koptyug, M Fekete… - Angewandte Chemie …, 2020 - Wiley Online Library
Imaging of gases is a major challenge for any modality including MRI. NMR and MRI signals
are directly proportional to the nuclear spin density and the degree of alignment of nuclear …
are directly proportional to the nuclear spin density and the degree of alignment of nuclear …
Order‐Unity 13C Nuclear Polarization of [1‐13C]Pyruvate in Seconds and the Interplay of Water and SABRE Enhancement
Abstract Signal Amplification By Reversible Exchange in SHield Enabled Alignment Transfer
(SABRE‐SHEATH) is investigated to achieve rapid hyperpolarization of 13C1 spins of [1 …
(SABRE‐SHEATH) is investigated to achieve rapid hyperpolarization of 13C1 spins of [1 …
Rapid 13C Hyperpolarization of the TCA Cycle Intermediate α-Ketoglutarate via SABRE-SHEATH
α-Ketoglutarate is a key biomolecule involved in a number of metabolic pathways─ most
notably the TCA cycle. Abnormal α-ketoglutarate metabolism has also been linked with …
notably the TCA cycle. Abnormal α-ketoglutarate metabolism has also been linked with …
Improving SABRE hyperpolarization with highly nonintuitive pulse sequences: Moving beyond avoided crossings to describe dynamics
Signal amplification by reversible exchange (SABRE) creates “hyperpolarization”(large spin
magnetization) using a transition metal catalyst and parahydrogen, addressing the …
magnetization) using a transition metal catalyst and parahydrogen, addressing the …
Development of a fully automated workstation for conducting routine SABRE hyperpolarization
SABRE is emerging as a fast, simple and low-cost hyperpolarization method because of its
ability to regenerate enhanced NMR signals. Generally, SABRE hyperpolarization has been …
ability to regenerate enhanced NMR signals. Generally, SABRE hyperpolarization has been …
Live magnetic observation of parahydrogen hyperpolarization dynamics
Hyperpolarized nuclear spins in molecules exhibit high magnetization that is unachievable
by classical polarization techniques, making them widely used as sensors in physics …
by classical polarization techniques, making them widely used as sensors in physics …
Low-frequency excitation of singlet–triplet transitions. Application to nuclear hyperpolarization
Coupled pairs of nuclear spin-1/2 support one singlet state and three triplet states.
Transitions between the singlet state and one of the triplet states may be driven by an …
Transitions between the singlet state and one of the triplet states may be driven by an …
[HTML][HTML] Magnetic shielding of parahydrogen hyperpolarization experiments for the masses
NMR techniques have inherent low sensitivity due to low nuclear spin polarization (P) or the
degree of alignment of nuclear spins with applied magnetic field. However, P can be …
degree of alignment of nuclear spins with applied magnetic field. However, P can be …
Interplay of Near-Zero-Field Dephasing, Rephasing, and Relaxation Dynamics and [1-13C]Pyruvate Polarization Transfer Efficiency in Pulsed SABRE-SHEATH
Hyperpolarized [1-13C] pyruvate is a revolutionary molecular probe enabling ultrafast
metabolic MRI scans in 1 min. This technology is now under evaluation in over 30 clinical …
metabolic MRI scans in 1 min. This technology is now under evaluation in over 30 clinical …