The ocean sampling day consortium

A Kopf, M Bicak, R Kottmann, J Schnetzer, I Kostadinov… - Gigascience, 2015 - Springer
Abstract Ocean Sampling Day was initiated by the EU-funded Micro B3 (Marine Microbial
Biodiversity, Bioinformatics, Biotechnology) project to obtain a snapshot of the marine …

Cell signaling model for arterial mechanobiology

L Irons, JD Humphrey - PLoS computational biology, 2020 - journals.plos.org
Arterial growth and remodeling at the tissue level is driven by mechanobiological processes
at cellular and sub-cellular levels. Although it is widely accepted that cells seek to promote …

[HTML][HTML] Synergistic effect of Aloe vera flower and Aloe gel on cutaneous wound healing targeting MFAP4 and its associated signaling pathway: In-vitro study

S Razia, H Park, E Shin, KS Shim, E Cho… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Aloe vera (L.) Burm. f.(Liliaceae family) is a well-known
traditional medicinal plant, that has been used to treat a variety of illnesses, for decades …

Role of ERK pathway in the pathogenesis of atopic dermatitis and its potential as a therapeutic target

N Zeze, M Kido-Nakahara, G Tsuji, E Maehara… - International journal of …, 2022 - mdpi.com
Atopic dermatitis (AD) is an eczematous skin disorder characterized by type 2 inflammation,
barrier disruption, and intense itch. In addition to type 2 cytokines, many other cytokines …

Open problems in mathematical biology

ST Vittadello, MPH Stumpf - Mathematical Biosciences, 2022 - Elsevier
Biology is data-rich, and it is equally rich in concepts and hypotheses. Part of trying to
understand biological processes and systems is therefore to confront our ideas and …

Analysis of sea star larval regeneration reveals conserved processes of whole-body regeneration across the metazoa

GA Cary, A Wolff, O Zueva, J Pattinato, VF Hinman - BMC biology, 2019 - Springer
Background Metazoan lineages exhibit a wide range of regenerative capabilities that vary
among developmental stage and tissue type. The most robust regenerative abilities are …

[HTML][HTML] The antiviral effects of a MEK1/2 inhibitor promote tumor regression in a preclinical model of human papillomavirus infection-induced tumorigenesis

AJ Luna, JM Young, RT Sterk, V Bondu, FA Schultz… - Antiviral Research, 2023 - Elsevier
Human papillomaviruses (HPVs) are a significant public health concern due to their
widespread transmission, morbidity, and oncogenic potential. Despite efficacious vaccines …

[HTML][HTML] Gentisic acid stimulates keratinocyte proliferation through ERK1/2 phosphorylation

M Kim, JG Kim, YK Shin, KY Kim - International Journal of Medical …, 2020 - ncbi.nlm.nih.gov
Keratinocyte proliferation is important for skin wound healing. The wound healing process
includes blood clotting around the wound, removal of dead cells and pathogens through …

Topical delivery of mitogen-activated protein kinase inhibitor binimetinib prevents the development of cutaneous neurofibromas in neurofibromatosis type 1 mutant …

F Coulpier, P Pulh, L Oubrou, J Naudet, L Fertitta… - Translational …, 2023 - Elsevier
Cutaneous neurofibromas (cNFs) are a hallmark of patients with the neurofibromatosis type
1 (NF1) genetic disorder. These benign nerve sheath tumors, which can amount to …

MAPK pathway involved in epidermal terminal differentiation of normal human epidermal keratinocytes

X Meng, L Qiu, H Song, N Dang - Open Medicine, 2018 - degruyter.com
Objective To investigate the effect of mitogen-activated protein kinase (MAPK) signaling
pathway in epidermal terminal differentiation. Methods The MAPK pathways (p38, ERK1/2 …