Tyrosinase is a copper-containing enzyme which is widely distributed in nature (eg, bacteria,
mammals, fungi) and involved in two consecutive steps of melanin biosynthesis. In humans …

The melanin pigments eumelanin (EM) and pheomelanin (PM), which are dark brown to
black and yellow to reddish-brown, respectively, are widely found among vertebrates. They …

The author identified the genes and proteins of human enzymes involved in the biosynthesis
of catecholamines (dopamine, norepinephrine, epinephrine) and tetrahydrobiopterin (BH4) …

The noradrenergic locus coeruleus (LC) is among the first regions of the brain affected by
pathology in both Alzheimer's disease (AD) and Parkinson's disease (PD), but the reasons …

A biomarker for declined methylation capacity is elevation of homocysteine levels. They
increase the risk for onset of vascular disease and contribute to progression of chronic …

The core pathological event in Parkinson's disease (PD) is the specific dying of dopamine
(DA) neurons of the substantia nigra pars compacta (SNc). The reasons why SNc DA …

Parkinson's disease is characterized by its distinct pathological features; loss of dopamine
neurons in the substantia nigra pars compacta and accumulation of Lewy bodies and Lewy …

Simple Summary This article examines the fascinating association between melanoma, a
malignant skin cancer, and Parkinson's disease (PD), a neurodegenerative disorder. Both …

Fascinatingly, an abundance of recent studies has subscribed to the importance of cytotoxic
immune mechanisms that appear to increase the risk/trigger for many progressive …

Progressive loss of dopaminergic neurons is the primary pathological feature of Parkinson's
disease (PD), which causes severe cognitive and motor dysfunction. In this context …