[HTML][HTML] Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention
With the advent of effective tools to study lipids, including mass spectrometry-based
lipidomics, lipids are emerging as central players in cancer biology. Lipids function as …
lipidomics, lipids are emerging as central players in cancer biology. Lipids function as …
Cannabinoids in the landscape of cancer
N Mangal, S Erridge, N Habib, A Sadanandam… - Journal of cancer …, 2021 - Springer
Introduction Cannabinoids are a group of terpenophenolic compounds derived from the
Cannabis sativa L. plant. There is a growing body of evidence from cell culture and animal …
Cannabis sativa L. plant. There is a growing body of evidence from cell culture and animal …
A guide to targeting the endocannabinoid system in drug design
A Stasiulewicz, K Znajdek, M Grudzień… - International journal of …, 2020 - mdpi.com
The endocannabinoid system (ECS) is one of the most crucial systems in the human
organism, exhibiting multi-purpose regulatory character. It is engaged in a vast array of …
organism, exhibiting multi-purpose regulatory character. It is engaged in a vast array of …
Antimicrobial and cytotoxic effects of cannabinoids: an updated review with future perspectives and current challenges
The development of new antibiotics is urgently needed to combat the threat of bacterial
resistance. New classes of compounds that have novel properties are urgently needed for …
resistance. New classes of compounds that have novel properties are urgently needed for …
Cannabinoids and prostate cancer: a systematic review of animal studies
Prostate cancer is a major cause of death among men worldwide. Recent preclinical
evidence implicates cannabinoids as powerful regulators of cell growth and differentiation …
evidence implicates cannabinoids as powerful regulators of cell growth and differentiation …
[HTML][HTML] Synthetic cannabinoids JWH-018, JWH-122, UR-144 and the phytocannabinoid THC activate apoptosis in placental cells
M Almada, P Alves, BM Fonseca, F Carvalho… - Toxicology letters, 2020 - Elsevier
The increasing use of synthetic cannabinoids (SCBs) in recreational settings is becoming a
new paradigm of drug abuse. Although SCBs effects mimic those of the Cannabis sativa …
new paradigm of drug abuse. Although SCBs effects mimic those of the Cannabis sativa …
Cannabinoids: Potential role in inflammatory and neoplastic skin diseases
R Milando, A Friedman - American journal of clinical dermatology, 2019 - Springer
The endocannabinoid system is a complex and nearly ubiquitous network of endogenous
ligands, enzymes, and receptors that can also be stimulated by exogenous compounds such …
ligands, enzymes, and receptors that can also be stimulated by exogenous compounds such …
Endocannabinoid system and tumour microenvironment: New intertwined connections for anticancer approaches
M Iozzo, G Sgrignani, G Comito, P Chiarugi… - Cells, 2021 - mdpi.com
The tumour microenvironment (TME) is now recognised as a hallmark of cancer, since
tumour: stroma crosstalk supports the key steps of tumour growth and progression. The …
tumour: stroma crosstalk supports the key steps of tumour growth and progression. The …
Targeting CYP2J2 to enhance the anti-glioma efficacy of cannabinoid receptor 2 stimulation by inhibiting the pro-angiogenesis function of M2 microglia
X Lei, X Chen, Y Quan, Y Tao, J Li - Frontiers in oncology, 2020 - frontiersin.org
Enhancing the therapeutic efficacy of anti-tumor drugs is essential for cancer management.
Although cannabinoid receptor 2 (CB2R) stimulation exerts anti-tumor action in glioma cells …
Although cannabinoid receptor 2 (CB2R) stimulation exerts anti-tumor action in glioma cells …
Antitumor cannabinoid chemotypes: Structural insights
P Morales, N Jagerovic - Frontiers in Pharmacology, 2019 - frontiersin.org
Cannabis has long been known to limit or prevent nausea and vomiting, lack of appetite,
and pain. For this reason, cannabinoids have been successfully used in the treatment of …
and pain. For this reason, cannabinoids have been successfully used in the treatment of …