Genistein: an integrative overview of its mode of action, pharmacological properties, and health benefits

J Sharifi-Rad, C Quispe, M Imran, A Rauf… - Oxidative medicine …, 2021 - Wiley Online Library
Genistein is an isoflavone first isolated from the brooming plant Dyer's Genista tinctoria L.
and is widely distributed in the Fabaceae family. As an isoflavone, mammalian genistein …

Biosensing chips for cancer diagnosis and treatment: a new wave towards clinical innovation

MJ Iqbal, Z Javed, J Herrera-Bravo, H Sadia… - Cancer Cell …, 2022 - Springer
Recent technological advances in nanoscience and material designing have led to the
development of point-of-care devices for biomolecule sensing and cancer diagnosis. In situ …

Therapeutic applications of curcumin nanomedicine formulations in cystic fibrosis

C Quispe, J Herrera-Bravo, K Khan, Z Javed… - Progress in …, 2022 - Springer
Medicinal applications of turmeric-derived curcumin have been known to mankind for long
ages. Its potential in managing “cystic fibrosis” has also been evaluated. This autosomal …

Reversal of brain aging by targeting telomerase: A nutraceutical approach

D Tsoukalas, AM Buga, AO Docea… - International …, 2021 - spandidos-publications.com
Telomeres, the protective caps of chromosomes, shorten with age, as telomerase, the
enzyme responsible for the compensation of telomere erosion, is inactive in the majority of …

Application of metabolomics in pediatric asthma: prediction, diagnosis and personalized treatment

MM Papamichael, C Katsardis, E Sarandi, S Georgaki… - Metabolites, 2021 - mdpi.com
Asthma in children remains a significant public health challenge affecting 5–20% of children
in Europe and is associated with increased morbidity and societal healthcare costs. The …

Prediction of autoimmune diseases by targeted metabolomic assay of urinary organic acids

D Tsoukalas, V Fragoulakis, E Papakonstantinou… - Metabolites, 2020 - mdpi.com
Autoimmune diseases (ADs) are chronic disorders characterized by the loss of self-
tolerance, and although being heterogeneous, they share common pathogenic …

Internet of medical things: an effective and fully automatic IoT approach using deep learning and fine-tuning to lung CT segmentation

LFF Souza, ICL Silva, AG Marques, FHS Silva… - Sensors, 2020 - mdpi.com
Several pathologies have a direct impact on society, causing public health problems.
Pulmonary diseases such as Chronic obstructive pulmonary disease (COPD) are already …

Metabolite alterations in autoimmune diseases: a systematic review of metabolomics studies

A Mujalli, WF Farrash, KS Alghamdi, AA Obaid - Metabolites, 2023 - mdpi.com
Autoimmune diseases, characterized by the immune system's loss of self-tolerance, lack
definitive diagnostic tests, necessitating the search for reliable biomarkers. This systematic …

Role of inflammatory lipid and fatty acid metabolic abnormalities induced by plastic additives exposure in childhood asthma

Z Chen, F Li, L Fu, Y Xia, Y Luo, A Guo, X Zhu… - Journal of …, 2024 - Elsevier
Lipid metabolism play an essential role in occurrence and development of asthma, and it
can be disturbed by phthalate esters (PAEs) and organophosphate flame retardants …

[HTML][HTML] The snapshot of metabolic health in evaluating micronutrient status, the risk of infection and clinical outcome of COVID-19

D Tsoukalas, E Sarandi, S Georgaki - Clinical Nutrition ESPEN, 2021 - Elsevier
COVID-19 has re-established the significance of analyzing the organism through a
metabolic perspective to uncover the dynamic interconnections within the biological …