Protein methylation, a post-translational modification (PTM), is observed in a wide variety of
cell types from prokaryotes to eukaryotes. With recent and rapid advancements in epigenetic …

Simple Summary Artificial intelligence (AI) technology has been advancing rapidly in recent
years and is being implemented in society. The medical field is no exception, and the clinical …

PRMT1, the major protein arginine methyltransferase in mammals, catalyzes
monomethylation and asymmetric dimethylation of arginine side chains in proteins. Initially …

Protein arginine methylation is a common post-translational modification involved in
numerous cellular processes including transcription, DNA repair, mRNA splicing and signal …

Protein arginine methylation is a common post-translational modification where a methyl
group is added onto arginine residues of a protein to alter detection by its binding partners …

Oxidative stress is known to be an inseparable factor involved in the presentation of liver
disorders. Free radicals interfere with DNA, proteins, and lipids, which are crucial in liver …

Protein methylation is one of the important post‐translational modifications. Although its
biological and physiological functions were unknown for a long time, we and others have …

Steroid receptors (SRs) are members of the nuclear hormonal receptor family, many of
which are transcription factors regulated by ligand binding. SRs regulate various human …

Accumulation of β-catenin in the nucleus is a hallmark of activation of the Wnt/β-catenin
signaling pathway, which drives development of a large proportion of human cancers …

A specific subtype of non‐small‐cell lung cancer (NSCLC) characterized with an EML 4‐
ALK fusion gene, which drives constitutive oncogenic activation of anaplastic lymphoma …