Context-specific regulation of extracellular vesicle biogenesis and cargo selection

AC Dixson, TR Dawson, D Di Vizio… - … Reviews Molecular Cell …, 2023 - nature.com
To coordinate, adapt and respond to biological signals, cells convey specific messages to
other cells. An important aspect of cell–cell communication involves secretion of molecules …

[HTML][HTML] Exosomes as a new frontier of cancer liquid biopsy

D Yu, Y Li, M Wang, J Gu, W Xu, H Cai, X Fang… - Molecular cancer, 2022 - Springer
Liquid biopsy, characterized by minimally invasive detection through biofluids such as
blood, saliva, and urine, has emerged as a revolutionary strategy for cancer diagnosis and …

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

JA Welsh, DCI Goberdhan, L O'Driscoll… - Journal of …, 2024 - Wiley Online Library
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …

[HTML][HTML] Review on strategies and technologies for exosome isolation and purification

J Chen, P Li, T Zhang, Z Xu, X Huang… - … in bioengineering and …, 2022 - frontiersin.org
Exosomes, a nano-sized subtype of extracellular vesicles secreted from almost all living
cells, are capable of transferring cell-specific constituents of the source cell to the recipient …

A brief history of nearly EV‐erything–The rise and rise of extracellular vesicles

Y Couch, EI Buzàs, D Di Vizio, YS Gho… - Journal of …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are small cargo‐bearing vesicles released by cells into the
extracellular space. The field of EVs has grown exponentially over the past two decades; this …

Identification of storage conditions stabilizing extracellular vesicles preparations

A Görgens, G Corso, DW Hagey… - Journal of …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) play a key role in many physiological and pathophysiological
processes and hold great potential for therapeutic and diagnostic use. Despite significant …

[HTML][HTML] Application of exosomes as liquid biopsy in clinical diagnosis

B Zhou, K Xu, X Zheng, T Chen, J Wang… - Signal transduction and …, 2020 - nature.com
Liquid biopsy refers to the sampling and molecular analysis of the biofluids of circulating
tumor cells, extracellular vesicles, nucleic acids, and so forth. Exosomes are small …

[HTML][HTML] RNA delivery by extracellular vesicles in mammalian cells and its applications

K O'Brien, K Breyne, S Ughetto, LC Laurent… - … reviews Molecular cell …, 2020 - nature.com
The term 'extracellular vesicles' refers to a heterogeneous population of vesicular bodies of
cellular origin that derive either from the endosomal compartment (exosomes) or as a result …

Detection of neuron-derived pathological α-synuclein in blood

A Kluge, J Bunk, E Schaeffer, A Drobny, W Xiang… - Brain, 2022 - academic.oup.com
To date, no reliable clinically applicable biomarker has been established for Parkinson's
disease. Our results indicate that a long anticipated blood test for Parkinson's disease may …

[HTML][HTML] Dosing extracellular vesicles

D Gupta, AM Zickler, S El Andaloussi - Advanced drug delivery reviews, 2021 - Elsevier
Extracellular vesicles (EVs) are natural nanoparticles containing biologically active
molecules. They are important mediators of intercellular communication and can be …